PDBe 1nsi

X-ray diffraction
2.55Å resolution

HUMAN INDUCIBLE NITRIC OXIDE SYNTHASE, ZN-BOUND, L-ARG COMPLEX

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nitric oxide synthase, inducible Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 431 amino acids
Theoretical weight: 49.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P35228 (Residues: 74-504)
Gene names: NOS2, NOS2A

Ligands and Environments


Cofactor: Ligand HEM 4 x HEM

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P43212
Unit cell:
a: 187.35Å b: 187.35Å c: 227.49Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.209 0.243
Expression system: Escherichia coli