› 1nrf

X-ray diffraction
2.5Å resolution

C-terminal domain of the Bacillus licheniformis BlaR penicillin-receptor

Released:
DOI: 10.2210/pdb1nrf/pdb
PDB entry 1nrf coloured by chain, front view.
PDB entry 1nrf coloured by chain, side view.
PDB entry 1nrf coloured by chain, top view.
Source organism: Bacillus licheniformis
Primary publication:
Crystal structure of the sensor domain of the BlaR penicillin receptor from Bacillus licheniformis.
Kerff F, Charlier P, Colombo ML, Sauvage E, Brans A, Frère JM, Joris B, Fonzé E
Biochemistry 42 12835-43 (2003)
PMID: 14596597

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146126 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulatory protein BlaR1 Chain: A
Molecule details ›
Chain: A
Length: 262 amino acids
Theoretical weight: 29.9 KDa
Source organism: Bacillus licheniformis
Expression system: Escherichia coli
UniProt:
  • Canonical: P12287 (Residues: 346-601; Coverage: 43%)
Gene names: blaR1, penR1
Sequence domains: Penicillin binding protein transpeptidase domain
Structure domains: DD-peptidase/beta-lactamase superfamily

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P41
Unit cell:
a: 45.848Å b: 45.848Å c: 130.198Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.204 0.257
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Cell envelope stress response in Gram-positive bacteria.
Jordan et al. (2008)
7 more

5 mentions without citation

Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates.
Docquier et al. (2010)
4 more