› › Function and Biology

OUTER MEMBRANE COBALAMIN TRANSPORTER (BTUB) FROM E. COLI, WITH BOUND CALCIUM AND CYANOCOBALAMIN (VITAMIN B12) SUBSTRATE

Source organism: Escherichia coli
Biochemical function: vitamin transmembrane transporter activity
Biological process: vitamin transmembrane transport
Cellular component: transmembrane transporter complex

Quick links

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00593
Domain description: TonB dependent receptor
Occurring in:
  1. Vitamin B12 transporter BtuB
The deposited structure of PDB entry 1nqh contains 1 copy of Pfam domain PF00593 (TonB dependent receptor) in Vitamin B12 transporter BtuB. Showing 1 copy in chain A.

PF07715
Domain description: TonB-dependent Receptor Plug Domain
Occurring in:
  1. Vitamin B12 transporter BtuB
The deposited structure of PDB entry 1nqh contains 1 copy of Pfam domain PF07715 (TonB-dependent Receptor Plug Domain) in Vitamin B12 transporter BtuB. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR010101
Domain description: TonB-dependent vitamin B12 transporter BtuB
Occurring in:
  1. Vitamin B12 transporter BtuB
IPR010917
Domain description: TonB-dependent receptor, conserved site
Occurring in:
  1. Vitamin B12 transporter BtuB
IPR000531
Domain description: TonB-dependent receptor-like, beta-barrel
Occurring in:
  1. Vitamin B12 transporter BtuB
IPR036942
Domain description: TonB-dependent receptor-like, beta-barrel domain superfamily
Occurring in:
  1. Vitamin B12 transporter BtuB
IPR012910
Domain description: TonB-dependent receptor, plug domain
Occurring in:
  1. Vitamin B12 transporter BtuB
IPR037066
Domain description: TonB-dependent receptor, plug domain superfamily
Occurring in:
  1. Vitamin B12 transporter BtuB
IPR039426
Domain description: TonB-dependent receptor-like
Occurring in:
  1. Vitamin B12 transporter BtuB

Structure domains

CATH CATH domains
2.40.170.20
Class: Mainly Beta
Architecture: Beta Barrel
Topology: Maltoporin; Chain A
Homology: TonB-dependent receptor, beta-barrel domain
Occurring in:
  1. Vitamin B12 transporter BtuB
The deposited structure of PDB entry 1nqh contains 1 copy of CATH domain 2.40.170.20 (Maltoporin; Chain A) in Vitamin B12 transporter BtuB. Showing 1 copy in chain A.
2.170.130.10
Class: Mainly Beta
Architecture: Beta Complex
Topology: Ferric Hydroxamate Uptake Protein; Chain A, domain 1
Homology: TonB-dependent receptor, plug domain
Occurring in:
  1. Vitamin B12 transporter BtuB
The deposited structure of PDB entry 1nqh contains 1 copy of CATH domain 2.170.130.10 (Ferric Hydroxamate Uptake Protein; Chain A, domain 1) in Vitamin B12 transporter BtuB. Showing 1 copy in chain A.
SCOP SCOP annotation
56948
Class: Membrane and cell surface proteins and peptides
Fold: Transmembrane beta-barrels
Superfamily: Porins
Occurring in:
  1. Vitamin B12 transporter BtuB
The deposited structure of PDB entry 1nqh contains 1 copy of SCOP domain 56948 (Ligand-gated protein channel) in Vitamin B12 transporter BtuB. Showing 1 copy in chain A.

Quick links