1npe

X-ray diffraction
2.3Å resolution

Crystal structure of Nidogen/Laminin Complex

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nidogen-1 Chain: A
Molecule details ›
Chain: A
Length: 267 amino acids
Theoretical weight: 30 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P10493 (Residues: 941-1207; Coverage: 22%)
Gene names: Ent, Nid1
Sequence domains: Low-density lipoprotein receptor repeat class B
Structure domains: TolB, C-terminal domain
Laminin subunit gamma-1 Chain: B
Molecule details ›
Chain: B
Length: 164 amino acids
Theoretical weight: 17.37 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P02468 (Residues: 769-932; Coverage: 10%)
Gene names: Lamb-2, Lamc-1, Lamc1
Sequence domains: Laminin EGF domain
Structure domains: Laminin

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 72.18Å b: 75.83Å c: 104.58Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.223 0.254
Expression system: Homo sapiens