X-ray diffraction
2.2Å resolution



Function and Biology Details

Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
DNA-directed DNA polymerase Chains: A, B
Molecule details ›
Chains: A, B
Length: 388 amino acids
Theoretical weight: 45.32 KDa
Source organism: Escherichia virus T4
Expression system: Escherichia coli
  • Canonical: P04415 (Residues: 1-388; Coverage: 43%)
Gene name: 43
Sequence domains: DNA polymerase family B, exonuclease domain
Structure domains:
DNA (5'-D(*TP*TP*T)-3') Chain: S
Molecule details ›
Chain: S
Length: 3 nucleotides
Theoretical weight: 868 Da
Source organism: Escherichia virus T4
Expression system: Not provided

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21212
Unit cell:
a: 114.701Å b: 109.656Å c: 70.268Å
α: 90° β: 90° γ: 90°
R R work R free
0.222 0.222 not available
Expression systems:
  • Escherichia coli
  • Not provided