1nko

X-ray diffraction
1.45Å resolution

Energetic and structural basis of sialylated oligosaccharide recognition by the natural killer cell inhibitory receptor p75/AIRM1 or Siglec-7

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sialic acid-binding Ig-like lectin 7 Chain: A
Molecule details ›
Chain: A
Length: 132 amino acids
Theoretical weight: 15.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y286 (Residues: 19-150; Coverage: 29%)
Gene names: AIRM1, SIGLEC7
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P21
Unit cell:
a: 32.461Å b: 49.715Å c: 39.787Å
α: 90° β: 113.08° γ: 90°
R-values:
R R work R free
0.277 0.277 0.301
Expression system: Escherichia coli