PDBe 1nda

X-ray diffraction
3.3Å resolution

THE STRUCTURE OF TRYPANOSOMA CRUZI TRYPANOTHIONE REDUCTASE IN THE OXIDIZED AND NADPH REDUCED STATE

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Trypanothione reductase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 491 amino acids
Theoretical weight: 53.8 KDa
Source organism: Trypanosoma cruzi
Expression system: Not provided
UniProt:
  • Canonical: P28593 (Residues: 2-492; Coverage: 100%)
Gene name: TPR
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand FAD 4 x FAD
No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 136.3Å b: 91.1Å c: 126Å
α: 90° β: 94° γ: 90°
R-values:
R R work R free
0.206 0.206 not available
Expression system: Not provided