Function and Biology Details
Reaction catalysed:
Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving Arg-|- bonds) as well as an endopeptidase.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Cathepsin H mini chain and Cystatin-A (preferred)
PDBe Complex ID:
PDB-CPX-129217 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Cathepsin H
Molecule details ›
Chains: A, B, C, D
Length: 220 amino acids
Theoretical weight: 24.33 KDa
Source organism: Sus scrofa
UniProt:
Sequence domains: Papain family cysteine protease
Structure domains: Cysteine proteinases
Length: 220 amino acids
Theoretical weight: 24.33 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
O46427 (Residues: 116-335; Coverage: 70%)
Sequence domains: Papain family cysteine protease
Structure domains: Cysteine proteinases
Cathepsin H mini chain
Molecule details ›
Chains: P, R, S, T
Length: 8 amino acids
Theoretical weight: 849 Da
Source organism: Sus scrofa
UniProt:
Length: 8 amino acids
Theoretical weight: 849 Da
Source organism: Sus scrofa
UniProt:
- Canonical: O46427 (Residues: 98-105; Coverage: 3%)
Cystatin-A
Molecule details ›
Chains: I, J, K, L
Length: 98 amino acids
Theoretical weight: 11.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Cystatin domain
Structure domains: Nuclear Transport Factor 2; Chain: A,
Length: 98 amino acids
Theoretical weight: 11.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P01040 (Residues: 1-98; Coverage: 100%)
Sequence domains: Cystatin domain
Structure domains: Nuclear Transport Factor 2; Chain: A,
