› 1n8v

X-ray diffraction
1.39Å resolution

Chemosensory Protein in complex with bromo-dodecanol

Released:
DOI: 10.2210/pdb1n8v/pdb
PDB 1n8v coloured by chain and viewed from the front.
PDB 1n8v coloured by chain and viewed from the side.
PDB 1n8v coloured by chain and viewed from the top.
Source organism: Mamestra brassicae
Primary publication:
Moth chemosensory protein exhibits drastic conformational changes and cooperativity on ligand binding.
Campanacci V, Lartigue A, Hällberg BM, Jones TA, Giudici-Orticoni MT, Tegoni M, Cambillau C
Proc. Natl. Acad. Sci. U.S.A. 100 5069-74 (2003)
PMID: 12697900

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chemosensory protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 112 amino acids
Theoretical weight: 13.09 KDa
Source organism: Mamestra brassicae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9NG96 (Residues: 17-128; Coverage: 100%)
Sequence domains: Insect pheromone-binding family, A10/OS-D
Structure domains: Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3

Ligands and Environments

1 bound ligand:
Ligand BDD 6 x BDD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21
Unit cell:
a: 33.46Å b: 54.18Å c: 56.38Å
α: 90° β: 93.88° γ: 90°
R-values:
R R work R free
0.181 0.18 0.202
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

Comprehensive History of CSP Genes: Evolution, Phylogenetic Distribution and Functions.
Liu et al. (2020)
5 more

9 mentions without citation

Moth chemosensory protein exhibits drastic conformational changes and cooperativity on ligand binding.
Campanacci et al. (2003)
8 more