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Solution structure of Pi4, a four disulfide bridged scorpion toxin active on potassium channels

Solution NMR
PDB entry 1n8m coloured by chain, ensemble of 10 models, front view.
PDB entry 1n8m coloured by chain, ensemble of 10 models, side view.
PDB entry 1n8m coloured by chain, ensemble of 10 models, top view.
Source organism: Pandinus imperator
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Potassium channel toxin alpha-KTx 6.4
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-157696

Macromolecules

Potassium channel toxin alpha-KTx 6.4
Chain: A
Length: 38 amino acids
Theoretical weight: 4.2 KDa
Source organism: Pandinus imperator
Expression system: Not provided
UniProt:
  • Canonical: P58498 (Residues: 1-38; Coverage: 100%)
Pfam: Scorpion short toxin, BmKK2
InterPro:
SCOP: Short-chain scorpion toxins
Potassium channel toxin alpha-KTx 6.4 in PDB entry 1n8m, assembly 1, front view.
Potassium channel toxin alpha-KTx 6.4 in PDB entry 1n8m, assembly 1, side view.
Potassium channel toxin alpha-KTx 6.4 in PDB entry 1n8m, assembly 1, top view.
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