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Structure and Ligand of a Histone Acetyltransferase Bromodomain

Solution NMR
PDB entry 1n72 coloured by chain, front view.
PDB entry 1n72 coloured by chain, side view.
PDB entry 1n72 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Histone acetyltransferase KAT2B
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-187769

Macromolecules

Histone acetyltransferase KAT2B
Chain: A
Length: 118 amino acids
Theoretical weight: 14.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q92831 (Residues: 719-832; Coverage: 14%)
Gene names: KAT2B, PCAF
Pfam: Bromodomain
InterPro:
CATH: Bromodomain-like
SCOP: Bromodomain
Histone acetyltransferase KAT2B in PDB entry 1n72, assembly 1, front view.
Histone acetyltransferase KAT2B in PDB entry 1n72, assembly 1, side view.
Histone acetyltransferase KAT2B in PDB entry 1n72, assembly 1, top view.
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