1n6h

X-ray diffraction
1.51Å resolution

Crystal Structure of Human Rab5a

Released:

Function and Biology Details

Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein Rab-5A Chain: A
Molecule details ›
Chain: A
Length: 170 amino acids
Theoretical weight: 18.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P20339 (Residues: 15-184; Coverage: 79%)
Gene names: RAB5, RAB5A
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 35.72Å b: 64.09Å c: 66.05Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.177 0.19
Expression system: Escherichia coli BL21(DE3)