X-ray diffraction
2.2Å resolution

Crystal structure of human saposin B

Source organism: Homo sapiens
Primary publication:
Crystal structure of saposin B reveals a dimeric shell for lipid binding.
Proc. Natl. Acad. Sci. U.S.A. 100 38-43 (2003)
PMID: 12518053

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Saposin-B Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 81 amino acids
Theoretical weight: 9.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P07602 (Residues: 195-273; Coverage: 16%)
Gene names: GLBA, PSAP, SAP1
Sequence domains:
Structure domains: Saposin-like

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P3121
Unit cell:
a: 72.14Å b: 72.14Å c: 94.366Å
α: 90° β: 90° γ: 120°
R R work R free
0.222 0.222 0.262
Expression system: Escherichia coli