X-ray diffraction
1.65Å resolution

Crystal structure of the alpha-X beta2 integrin I domain

Source organism: Homo sapiens
Primary publication:
Structure and allosteric regulation of the alpha X beta 2 integrin I domain.
Proc. Natl. Acad. Sci. U.S.A. 100 1873-8 (2003)
PMID: 12554829

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Integrin alpha-X Chain: A
Molecule details ›
Chain: A
Length: 198 amino acids
Theoretical weight: 22.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P20702 (Residues: 147-338; Coverage: 17%)
Gene names: CD11C, ITGAX
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS
Spacegroup: P61
Unit cell:
a: 84.694Å b: 84.694Å c: 65.776Å
α: 90° β: 90° γ: 120°
R R work R free
0.209 0.208 0.225
Expression system: Escherichia coli BL21(DE3)