1mzh

X-ray diffraction
2Å resolution

QR15, an Aldolase

Released:
Source organism: Aquifex aeolicus
Entry authors: Tan AY, Smith PC, Shen J, Xiao R, Acton T, Rost B, Montelione G, Hunt JF, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Reaction catalysed:
2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Deoxyribose-phosphate aldolase Chains: A, B
Molecule details ›
Chains: A, B
Length: 225 amino acids
Theoretical weight: 25.01 KDa
Source organism: Aquifex aeolicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O66540 (Residues: 1-219; Coverage: 100%)
Gene names: aq_148, deoC
Sequence domains: DeoC/LacD family aldolase
Structure domains: Aldolase class I

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: C2221
Unit cell:
a: 49.139Å b: 123.458Å c: 151.822Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.223 0.277
Expression system: Escherichia coli