› 1mr6

Solution NMR

Solution Structure of gamma-Bungarotoxin:Implication for the role of the Residues Adjacent to RGD in Integrin Binding

Released:
DOI: 10.2210/pdb1mr6/pdb
PDB entry 1mr6 coloured by chain, ensemble of 20 models, front view.
PDB entry 1mr6 coloured by chain, ensemble of 20 models, side view.
PDB entry 1mr6 coloured by chain, ensemble of 20 models, top view.
Source organism: Bungarus multicinctus
Primary publication:
Solution structure of gamma-bungarotoxin: the functional significance of amino acid residues flanking the RGD motif in integrin binding.
Shiu JH, Chen CY, Chang LS, Chen YC, Chen YC, Lo YH, Liu YC, Chuang WJ
Proteins 57 839-49 (2004)
PMID: 15390258

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195504 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gamma-bungarotoxin Chain: A
Molecule details ›
Chain: A
Length: 68 amino acids
Theoretical weight: 7.55 KDa
Source organism: Bungarus multicinctus
UniProt:
  • Canonical: Q9YGJ0 (Residues: 22-89; Coverage: 100%)
Sequence domains: Snake toxin and toxin-like protein
Structure domains: CD59

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing

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Citations

8 review citations

Venomics: a new paradigm for natural products-based drug discovery.
Vetter et al. (2011)
7 more

5 mentions without citation

Solution structure and phylogenetics of Prod1, a member of the three-finger protein superfamily implicated in salamander limb regeneration.
Garza-Garcia et al. (2009)
4 more