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SMALL G-PROTEIN

Source organism: Homo sapiens
Biochemical function: Rho GDP-dissociation inhibitor binding
Biological process: regulation of neutrophil migration
Cellular component: ficolin-1-rich granule membrane

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EC 3.6.5.2: Small monomeric GTPase

Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Systematic name:
GTP phosphohydrolase (cell-regulating)

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00071
Domain description: Ras family
Occurring in:
  1. Ras-related C3 botulinum toxin substrate 1
The deposited structure of PDB entry 1mh1 contains 1 copy of Pfam domain PF00071 (Ras family) in Ras-related C3 botulinum toxin substrate 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001806
Domain description: Small GTPase
Occurring in:
  1. Ras-related C3 botulinum toxin substrate 1
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Ras-related C3 botulinum toxin substrate 1
IPR005225
Domain description: Small GTP-binding protein domain
Occurring in:
  1. Ras-related C3 botulinum toxin substrate 1
IPR003578
Domain description: Small GTPase Rho
Occurring in:
  1. Ras-related C3 botulinum toxin substrate 1

Structure domain

CATH CATH domain
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. Ras-related C3 botulinum toxin substrate 1
The deposited structure of PDB entry 1mh1 contains 1 copy of CATH domain 3.40.50.300 (Rossmann fold) in Ras-related C3 botulinum toxin substrate 1. Showing 1 copy in chain A.
SCOP SCOP annotation
52592
Class: Alpha and beta proteins (a/b)
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Occurring in:
  1. Ras-related C3 botulinum toxin substrate 1
The deposited structure of PDB entry 1mh1 contains 1 copy of SCOP domain 52592 (G proteins) in Ras-related C3 botulinum toxin substrate 1. Showing 1 copy in chain A.

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