EC 3.6.5.2: Small monomeric GTPase
Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Systematic name:
GTP phosphohydrolase (cell-regulating)
GO terms
Biochemical function:
Biological process:
- regulation of neutrophil migration
- positive regulation of substrate adhesion-dependent cell spreading
- ruffle assembly
- positive regulation of neutrophil chemotaxis
- semaphorin-plexin signaling pathway
- cell chemotaxis
- regulation of respiratory burst
- Wnt signaling pathway, planar cell polarity pathway
- positive regulation of focal adhesion assembly
- localization within membrane
- positive regulation of stress fiber assembly
- regulation of stress fiber assembly
- localization
- cell motility
- negative regulation of receptor-mediated endocytosis
- hepatocyte growth factor receptor signaling pathway
- respiratory burst
- regulation of nitric oxide biosynthetic process
- engulfment of apoptotic cell
- intracellular signal transduction
- positive regulation of Rho protein signal transduction
- substrate adhesion-dependent cell spreading
- regulation of actin cytoskeleton organization
- negative regulation of interleukin-23 production
- ruffle organization
- positive regulation of microtubule polymerization
- cortical cytoskeleton organization
- regulation of cell migration
- actin filament polymerization
- actin cytoskeleton organization
- lamellipodium assembly
- cell projection assembly
- Rac protein signal transduction
- cell migration
- positive regulation of cell-substrate adhesion
- negative regulation of fibroblast migration
- positive regulation of endothelial cell migration
- positive regulation of lamellipodium assembly
- regulation of lamellipodium assembly
- regulation of hydrogen peroxide metabolic process
- anatomical structure morphogenesis
- response to wounding
- regulation of cell size
- regulation of cell shape
- motor neuron axon guidance
- small GTPase-mediated signal transduction
- establishment or maintenance of cell polarity
- cell-matrix adhesion
- cell adhesion
- actin filament organization
- inflammatory response
- sphingosine-1-phosphate receptor signaling pathway
- positive regulation of protein phosphorylation
- neuron migration
Cellular component:
- ficolin-1-rich granule membrane
- glutamatergic synapse
- postsynapse
- extracellular exosome
- recycling endosome membrane
- synapse
- dendritic spine
- NADPH oxidase complex
- cell projection
- melanosome
- cytoplasmic ribonucleoprotein granule
- ruffle membrane
- cytoplasmic vesicle
- secretory granule membrane
- dendrite
- lamellipodium
- membrane
- cell cortex
- focal adhesion
- plasma membrane
- actin filament
- cytoskeleton
- cytosol
- trans-Golgi network
- endoplasmic reticulum membrane
- cytoplasm
- nucleus