Function and Biology

1.65 A Structure of Cleaved Viral Serpin CRMA

Source organism: Cowpox virus
Biochemical function: serine-type endopeptidase inhibitor activity
Biological process: not assigned
Cellular component: extracellular space

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00079
Domain description: Serpin (serine protease inhibitor)
Occurring in:
  1. Serine proteinase inhibitor 2
The deposited structure of PDB entry 1m93 contains 1 copy of Pfam domain PF00079 (Serpin (serine protease inhibitor)) in Serine proteinase inhibitor 2. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR036186
IPR023796
Domain description: Serpin domain
Occurring in:
  1. Serine proteinase inhibitor 2
  2. Serine proteinase inhibitor 2
IPR042185
Domain description: Serpin superfamily, domain 2
Occurring in:
  1. Serine proteinase inhibitor 2
  2. Serine proteinase inhibitor 2
IPR023795
Domain description: Serpin, conserved site
Occurring in:
  1. Serine proteinase inhibitor 2
IPR042178
Domain description: Serpin superfamily, domain 1
Occurring in:
  1. Serine proteinase inhibitor 2
IPR000215
Domain description: Serpin family
Occurring in:
  1. Serine proteinase inhibitor 2

Structure domains

CATH CATH domains
3.30.497.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Antithrombin; Chain I, domain 2
Homology: Antithrombin, subunit I, domain 2
Occurring in:
  1. Serine proteinase inhibitor 2
The deposited structure of PDB entry 1m93 contains 1 copy of CATH domain 3.30.497.10 (Antithrombin; Chain I, domain 2) in Serine proteinase inhibitor 2. Showing 1 copy in chain B.
2.30.39.10
Class: Mainly Beta
Architecture: Roll
Topology: Alpha-1-antitrypsin; domain 1
Homology: Alpha-1-antitrypsin, domain 1
Occurring in:
  1. Serine proteinase inhibitor 2
The deposited structure of PDB entry 1m93 contains 1 copy of CATH domain 2.30.39.10 (Alpha-1-antitrypsin; domain 1) in Serine proteinase inhibitor 2. Showing 1 copy in chain B.
1.10.287.580
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Helix Hairpins
Homology: Helix hairpin bin
Occurring in:
  1. Serine proteinase inhibitor 2
The deposited structure of PDB entry 1m93 contains 1 copy of CATH domain 1.10.287.580 (Helix Hairpins) in Serine proteinase inhibitor 2. Showing 1 copy in chain A.
SCOP SCOP annotation
56575
Class: Multi-domain proteins (alpha and beta)
Fold: Serpins
Superfamily: Serpins
Occurring in:
  1. Serine proteinase inhibitor 2
  2. Serine proteinase inhibitor 2
  3. Serine proteinase inhibitor 2
The deposited structure of PDB entry 1m93 contains 1 copy of SCOP domain 56575 (Serpins) in Serine proteinase inhibitor 2. Showing 1 copy in chain A.