1m8o

Solution NMR

Platelet integrin alfaIIb-beta3 cytoplasmic domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrin alpha-IIb light chain, form 2 Chain: A
Molecule details ›
Chain: A
Length: 20 amino acids
Theoretical weight: 2.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P08514 (Residues: 1020-1039; Coverage: 2%)
Gene names: GP2B, ITGA2B, ITGAB
Sequence domains: Integrin alpha cytoplasmic region
Integrin beta-3 Chain: B
Molecule details ›
Chain: B
Length: 47 amino acids
Theoretical weight: 5.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P05106 (Residues: 742-788; Coverage: 6%)
Gene names: GP3A, ITGB3
Sequence domains: Integrin beta cytoplasmic domain
Structure domains: Integrin beta subunit, cytoplasmic domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)