Solution NMR

Solution structure of a circular form of the N-terminal SH3 domain (E132C, E133G, R191G mutant) from oncogene protein c-Crk

Source organism: Mus musculus
Entry authors: Schumann FH, Varadan R, Tayakuniyil PP, Hall JB, Camarero JA, Fushman D

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Adapter molecule crk Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 7.03 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: Q64010 (Residues: 132-191; Coverage: 20%)
Gene names: Crk, Crko
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Simulated annealing combined with torsion angle dynamics
Expression system: Escherichia coli