PDBe 1m11

Electron Microscopy
16Å resolution

structural model of human decay-accelerating factor bound to echovirus 7 from cryo-electron microscopy

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero 240-mer (preferred)
hetero tetramer
hetero 20-mer
hetero 24-mer
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Complement decay-accelerating factor Chain: R
Molecule details ›
Chain: R
Length: 243 amino acids
Theoretical weight: 27.02 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P08174 (Residues: 35-277; Coverage: 70%)
Gene names: CD55, CR, DAF
Sequence domains: Sushi repeat (SCR repeat)
COAT PROTEIN VP1 Chain: 1
Molecule details ›
Chain: 1
Length: 278 amino acids
Theoretical weight: 31.68 KDa
Source organism: Echovirus E7
Expression system: Homo sapiens
UniProt:
  • Canonical: Q914E0 (Residues: 569-846; Coverage: 13%)
Sequence domains: picornavirus capsid protein
COAT PROTEIN VP2 Chain: 2
Molecule details ›
Chain: 2
Length: 254 amino acids
Theoretical weight: 28.44 KDa
Source organism: Echovirus E7
Expression system: Homo sapiens
UniProt:
  • Canonical: Q914E0 (Residues: 77-330; Coverage: 12%)
Sequence domains: picornavirus capsid protein
COAT PROTEIN VP3 Chain: 3
Molecule details ›
Chain: 3
Length: 238 amino acids
Theoretical weight: 26.26 KDa
Source organism: Echovirus E7
Expression system: Homo sapiens
UniProt:
  • Canonical: Q914E0 (Residues: 331-568; Coverage: 11%)
Sequence domains: picornavirus capsid protein

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 16Å
Expression systems:
  • Komagataella pastoris
  • Homo sapiens