1ly2

X-ray diffraction
1.8Å resolution

Crystal structure of unliganded human CD21 SCR1-SCR2 (Complement receptor type 2)

Released:
Source organism: Homo sapiens
Primary publication:
The crystal structure of human CD21: Implications for Epstein-Barr virus and C3d binding.
Proc. Natl. Acad. Sci. U.S.A. 99 10641-6 (2002)
PMID: 12122212

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Complement receptor type 2 Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 14.26 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P20023 (Residues: 22-148; Coverage: 13%)
Gene names: C3DR, CR2
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P1
Unit cell:
a: 31.6Å b: 33.27Å c: 42.11Å
α: 91.51° β: 111.44° γ: 117.81°
R-values:
R R work R free
0.179 0.179 0.234
Expression system: Komagataella pastoris