Solution NMR

Solution structure of alpha-cobratoxin complexed with a cognate peptide (structure ensemble)


Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Alpha-cobratoxin Chain: A
Molecule details ›
Chain: A
Length: 71 amino acids
Theoretical weight: 7.84 KDa
Source organism: Naja kaouthia
  • Canonical: P01391 (Residues: 1-71; Coverage: 100%)
Structure domains: CD59
Acetylcholine receptor subunit alpha Chain: B
Molecule details ›
Chain: B
Length: 19 amino acids
Theoretical weight: 2.42 KDa
Source organism: Tetronarce californica
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P02710 (Residues: 205-222; Coverage: 4%)
Gene name: CHRNA1

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry and simulated annealing
Expression system: Escherichia coli BL21(DE3)