X-ray diffraction
2.9Å resolution

Function and Biology Details

Reactions catalysed:
ATP + 1-(beta-D-ribofuranosyl)-nicotinamide = ADP + beta-nicotinamide D-ribonucleotide
ATP + nicotinamide ribonucleotide = diphosphate + NAD(+)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Bifunctional NAD biosynthesis protein NadR Chain: A
Molecule details ›
Chain: A
Length: 365 amino acids
Theoretical weight: 42.95 KDa
Source organism: Haemophilus influenzae
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P44308 (Residues: 57-421; Coverage: 87%)
Gene names: HI_0763, nadR
Structure domains:

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12B
Spacegroup: P6422
Unit cell:
a: 106.871Å b: 106.871Å c: 174.945Å
α: 90° β: 90° γ: 120°
R R work R free
0.236 0.236 0.298
Expression system: Escherichia coli BL21(DE3)