› 1lvk

X-ray diffraction
1.9Å resolution

X-RAY CRYSTAL STRUCTURE OF THE MG (DOT) 2'(3')-O-(N-METHYLANTHRANILOYL) NUCLEOTIDE BOUND TO DICTYOSTELIUM DISCOIDEUM MYOSIN MOTOR DOMAIN

Released:
DOI: 10.2210/pdb1lvk/pdb
PDB entry 1lvk coloured by chain, front view.
PDB entry 1lvk coloured by chain, side view.
PDB entry 1lvk coloured by chain, top view.
Source organism: Dictyostelium discoideum
Primary publication:
X-ray crystal structure and solution fluorescence characterization of Mg.2'(3')-O-(N-methylanthraniloyl) nucleotides bound to the Dictyostelium discoideum myosin motor domain.
Bauer CB, Kuhlman PA, Bagshaw CR, Rayment I
J Mol Biol 274 394-407 (1997)
PMID: 9405148

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140379 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myosin-2 heavy chain Chain: A
Molecule details ›
Chain: A
Length: 762 amino acids
Theoretical weight: 86.75 KDa
Source organism: Dictyostelium discoideum
Expression system: Dictyostelium discoideum
UniProt:
  • Canonical: P08799 (Residues: 1-759; Coverage: 36%)
Gene names: DDB_G0286355, mhcA
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand MG 1 x MG
Ligand MNT 1 x MNT
Ligand BEF 1 x BEF
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P21212
Unit cell:
a: 103.9Å b: 179.9Å c: 53.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.2 not available
Expression system: Dictyostelium discoideum

Quick links

Citations

2 review citations

The motor mechanism of myosin V: insights for muscle contraction.
Sweeney et al. (2004)
1 more

6 mentions without citation

Probing the local dynamics of nucleotide-binding pocket coupled to the global dynamics: myosin versus kinesin.
Zheng et al. (2005)
5 more