Structure analysis

Aquifex aeolicus KDO8P synthase H185G mutant in complex with Cadmium

X-ray diffraction
2.1Å resolution
Source organism: Aquifex aeolicus
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo tetramer
Accessible surface area: 34100 Å2
Buried surface area: 15300 Å2
Dissociation area: 3,000 Å2
Dissociation energy (ΔGdiss): 40 kcal/mol
Dissociation entropy (TΔSdiss): 15 kcal/mol
Interface energy (ΔGint): -134 kcal/mol
Symmetry number: 4

Macromolecules

Chains: A, B
Length: 267 amino acids
Theoretical weight: 29.69 KDa
Source organism: Aquifex aeolicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O66496 (Residues: 1-267; Coverage: 100%)
Gene names: aq_085, kdsA
Pfam: DAHP synthetase I family
InterPro:
CATH: Aldolase class I
SCOP: Class I DAHP synthetase

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