1lki

X-ray diffraction
2Å resolution

THE CRYSTAL STRUCTURE AND BIOLOGICAL FUNCTION OF LEUKEMIA INHIBITORY FACTOR: IMPLICATIONS FOR RECEPTOR BINDING

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Leukemia inhibitory factor Chain: A
Molecule details ›
Chain: A
Length: 180 amino acids
Theoretical weight: 19.89 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P09056 (Residues: 24-203; Coverage: 100%)
Gene name: Lif
Sequence domains: LIF / OSM family
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 31.1Å b: 56.2Å c: 95.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.186 not available
Expression system: Escherichia coli