X-ray diffraction
1.8Å resolution



Function and Biology Details

Reaction catalysed:
Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
Uracil-DNA glycosylase Chain: E
Molecule details ›
Chain: E
Length: 244 amino acids
Theoretical weight: 27.37 KDa
Source organism: Human alphaherpesvirus 1
  • Canonical: P10186 (Residues: 91-334; Coverage: 73%)
Gene name: UL2
Sequence domains: Uracil DNA glycosylase superfamily
Structure domains: Uracil-DNA glycosylase-like domain
DNA (5'-D(*TP*TP*T)-3') Chain: D
Molecule details ›
Chain: D
Length: 3 nucleotides
Theoretical weight: 868 Da
Source organism: Human alphaherpesvirus 1
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 46.66Å b: 61.83Å c: 86.67Å
α: 90° β: 90° γ: 90°
R R work R free
0.174 0.174 0.225
Expression system: Not provided