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Structure of the Retinal Determination Protein Dachshund Reveals a DNA-Binding Motif

X-ray diffraction
1.65Å resolution
PDB entry 1l8r coloured by chain, front view.
PDB entry 1l8r coloured by chain, side view.
PDB entry 1l8r coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Dachshund homolog 1
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-193777
Assembly 2
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Assembly Name: Dachshund homolog 1
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-193777

Macromolecules

Dachshund homolog 1
Chains: A, B
Length: 101 amino acids
Theoretical weight: 11.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UI36 (Residues: 184-282; Coverage: 13%)
Gene names: DACH, DACH1
Pfam: SKI/SNO/DAC family
InterPro:
CATH: Ski
SCOP: Dachshund-homology domain
Dachshund homolog 1 in PDB entry 1l8r, assembly 1, front view.
Dachshund homolog 1 in PDB entry 1l8r, assembly 1, side view.
Dachshund homolog 1 in PDB entry 1l8r, assembly 1, top view.
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