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Rad50 coiled-coil Zn hook

X-ray diffraction
2.2Å resolution
PDB entry 1l8d coloured by chain, front view.
PDB entry 1l8d coloured by chain, side view.
PDB entry 1l8d coloured by chain, top view.
Source organism: Pyrococcus furiosus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: DNA double-strand break repair Rad50 ATPase
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Multimeric state: homo dimer
Accessible surface area: 14608.2 Å2
Buried surface area: 2464.57 Å2
Dissociation area: 759.44 Å2
Dissociation energy (ΔGdiss): 25.25 kcal/mol
Dissociation entropy (TΔSdiss): 13.36 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-157668

Macromolecules

DNA double-strand break repair Rad50 ATPase
Chains: A, B
Length: 112 amino acids
Theoretical weight: 13.15 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli
UniProt:
  • Canonical: P58301 (Residues: 395-506; Coverage: 13%)
Gene names: PF1167, rad50
Pfam: Rad50 zinc hook motif
InterPro: RAD50, zinc hook
CATH: Helix hairpin bin
SCOP: Rad50 coiled-coil Zn hook
DNA double-strand break repair Rad50 ATPase in PDB entry 1l8d, assembly 1, front view.
DNA double-strand break repair Rad50 ATPase in PDB entry 1l8d, assembly 1, side view.
DNA double-strand break repair Rad50 ATPase in PDB entry 1l8d, assembly 1, top view.
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