› 1l5b

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyanovirin-N Chains: A, B
Molecule details ›
Chains: A, B
Length: 101 amino acids
Theoretical weight: 11.02 KDa
Source organism: Nostoc ellipsosporum
Expression system: Escherichia coli
UniProt:
  • Canonical: P81180 (Residues: 1-101; Coverage: 100%)
Sequence domains: CVNH domain
Structure domains: Cyanovirin-N

Ligands and Environments

2 bound ligands:
Ligand NA 1 x NA
Ligand NHE 1 x NHE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: P41212
Unit cell:
a: 61.966Å b: 61.966Å c: 148.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.247 0.247 0.258
Expression system: Escherichia coli

Quick links

Citations

16 review citations

Evaluation of Microalgae Antiviral Activity and Their Bioactive Compounds.
Carbone et al. (2021)
15 more

11 mentions without citation

An update of the recombinant protein expression systems of Cyanovirin-N and challenges of preclinical development.
Lotfi et al. (2018)
10 more