1kxu

X-ray diffraction
2.6Å resolution

CYCLIN H, A POSITIVE REGULATORY SUBUNIT OF CDK ACTIVATING KINASE

Released:
Source organism: Homo sapiens
Entry authors: Kim KK, Chamberin HM, Morgan DO, Kim S-H

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyclin-H Chain: A
Molecule details ›
Chain: A
Length: 333 amino acids
Theoretical weight: 38.89 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P51946 (Residues: 1-323; Coverage: 100%)
Gene name: CCNH
Sequence domains:
Structure domains: Cyclin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL1-5
Spacegroup: I4122
Unit cell:
a: 84.08Å b: 84.08Å c: 374.88Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.214 0.295
Expression system: Spodoptera frugiperda