Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Superantigen, staphylococcal/streptococcal toxin, bacterial
- Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site
- Staphylococcal/streptococcal toxin, bacterial
- Immunoglobulin C1-set
- Immunoglobulin V-set domain
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin-like fold
5 more domains
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
Exotoxin type C and TR-beta light chain (preferred)
PDBe Complex ID:
PDB-CPX-134787 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Exotoxin type C
Molecule details ›
Chains: A, B, C, D
Length: 208 amino acids
Theoretical weight: 24.38 KDa
Source organism: Streptococcus pyogenes
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 208 amino acids
Theoretical weight: 24.38 KDa
Source organism: Streptococcus pyogenes
Expression system: Escherichia coli
UniProt:
- Canonical:
Q8NKX2 (Residues: 28-235; Coverage: 100%)
Sequence domains:
- Staphylococcal/Streptococcal toxin, OB-fold domain
- Staphylococcal/Streptococcal toxin, beta-grasp domain
T cell receptor beta constant 1
Molecule details ›
Chains: E, F
Length: 247 amino acids
Theoretical weight: 27.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Length: 247 amino acids
Theoretical weight: 27.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P01850 (Residues: 1-129; Coverage: 73%)
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
CHESS BEAMLINE A1
Spacegroup:
P21
Expression system: Escherichia coli
