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X-ray diffraction
2.15Å resolution

X-ray Structure Of Der P 2, The Major House Dust Mite Allergen

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mite group 2 allergen Der p 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 129 amino acids
Theoretical weight: 14.12 KDa
Source organism: Dermatophagoides pteronyssinus
Expression system: Escherichia coli
UniProt:
  • Canonical: P49278 (Residues: 18-146; Coverage: 100%)
Gene name: DERP2
Sequence domains: ML domain
Structure domains: Immunoglobulin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B, EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P2221
Unit cell:
a: 71.692Å b: 108.747Å c: 91.971Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 0.27
Expression system: Escherichia coli