X-ray diffraction
1.9Å resolution

Human methionine aminopeptidase type II in complex with L-methionine

Source organism: Homo sapiens
Primary publication:
Human methionine aminopeptidase type 2 in complex with L- and D-methionine.
Bioorg. Med. Chem. Lett. 16 2580-3 (2006)
PMID: 16540317

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Methionine aminopeptidase 2 Chain: A
Molecule details ›
Chain: A
Length: 478 amino acids
Theoretical weight: 52.99 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
  • Canonical: P50579 (Residues: 1-478; Coverage: 100%)
Gene names: METAP2, MNPEP, P67EIF2
Sequence domains: Metallopeptidase family M24
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: C2221
Unit cell:
a: 90.069Å b: 98.66Å c: 101.37Å
α: 90° β: 90° γ: 90°
R R work R free
0.179 0.178 0.207
Expression system: Spodoptera frugiperda