› › Function and Biology

SOLUTION STRUCTURE OF TGF-B1, NMR, MINIMIZED AVERAGE STRUCTURE

Source organism: Homo sapiens
Biochemical function: growth factor activity
Biological process: not assigned
Cellular component: extracellular region

Quick links

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00019
Domain description: Transforming growth factor beta like domain
Occurring in:
  1. Transforming growth factor beta-1
The deposited structure of PDB entry 1klc contains 2 copies of Pfam domain PF00019 (Transforming growth factor beta like domain) in Transforming growth factor beta-1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001839
Domain description: Transforming growth factor-beta, C-terminal
Occurring in:
  1. Transforming growth factor beta-1
IPR029034
Domain description: Cystine-knot cytokine
Occurring in:
  1. Transforming growth factor beta-1
IPR017948
Domain description: Transforming growth factor beta, conserved site
Occurring in:
  1. Transforming growth factor beta-1
IPR015615
Domain description: Transforming growth factor-beta-related
Occurring in:
  1. Transforming growth factor beta-1

Structure domain

CATH CATH domain
2.10.90.10
Class: Mainly Beta
Architecture: Ribbon
Topology: Cystine Knot Cytokines, subunit B
Homology: Cystine-knot cytokines
Occurring in:
  1. Transforming growth factor beta-1
The deposited structure of PDB entry 1klc contains 2 copies of CATH domain 2.10.90.10 (Cystine Knot Cytokines, subunit B) in Transforming growth factor beta-1. Showing 1 copy in chain A.
SCOP SCOP annotation
57507
Class: Small proteins
Fold: Cystine-knot cytokines
Superfamily: Cystine-knot cytokines
Occurring in:
  1. Transforming growth factor beta-1
The deposited structure of PDB entry 1klc contains 2 copies of SCOP domain 57507 (Transforming growth factor (TGF)-beta) in Transforming growth factor beta-1. Showing 1 copy in chain A.

Quick links