› 1kbf

Solution NMR

Solution Structure of the Cysteine-Rich C1 Domain of Kinase Suppressor of Ras

Released:
DOI: 10.2210/pdb1kbf/pdb
PDB entry 1kbf coloured by chain, ensemble of 20 models, front view.
PDB entry 1kbf coloured by chain, ensemble of 20 models, side view.
PDB entry 1kbf coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR).
Zhou M, Horita DA, Waugh DS, Byrd RA, Morrison DK
J Mol Biol 315 435-46 (2002)
PMID: 11786023

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178857 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinase suppressor of Ras 1 Chain: A
Molecule details ›
Chain: A
Length: 49 amino acids
Theoretical weight: 5.58 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q61097 (Residues: 331-378; Coverage: 6%)
Gene names: Ksr, Ksr1
Structure domains: Wheat Germ Agglutinin (Isolectin 2); domain 1

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 68%
Refinement method: molecular dynamics
Expression system: Escherichia coli BL21

Quick links

Citations

24 review citations

Regulation of MAP kinase signaling modules by scaffold proteins in mammals.
Morrison et al. (2003)
23 more

1 mention without citation

Structural bioinformatics prediction of membrane-binding proteins.
Bhardwaj et al. (2006)