X-ray diffraction
1.9Å resolution

Complex of DC-SIGNR and GlcNAc2Man3


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
C-type lectin domain family 4 member M Chains: A, B
Molecule details ›
Chains: A, B
Length: 139 amino acids
Theoretical weight: 16.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9H2X3 (Residues: 262-399; Coverage: 35%)
Gene names: CD209L, CD209L1, CD299, CLEC4M
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

Carbohydrate polymer : NEW Components: MAN, NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X26C
Spacegroup: P212121
Unit cell:
a: 50.226Å b: 57.039Å c: 89.263Å
α: 90° β: 90° γ: 90°
R R work R free
0.194 0.194 0.24
Expression system: Escherichia coli