X-ray diffraction
2.5Å resolution

Crystal Structure of the Acyl-homoserinelactone Synthase EsaI Complexed with Rhenate


Function and Biology Details

Reaction catalysed:
An acyl-[acyl-carrier-protein] + S-adenosyl-L-methionine = [acyl-carrier-protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Acyl-homoserine-lactone synthase Chain: A
Molecule details ›
Chain: A
Length: 230 amino acids
Theoretical weight: 26.04 KDa
Source organism: Pantoea stewartii subsp. stewartii
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P54656 (Residues: 1-210; Coverage: 100%)
Gene name: esaI
Sequence domains: Autoinducer synthase
Structure domains: Aminopeptidase

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P43
Unit cell:
a: 66.39Å b: 66.39Å c: 47.325Å
α: 90° β: 90° γ: 90°
R R work R free
0.222 0.216 0.275
Expression system: Escherichia coli BL21(DE3)