1k2i

X-ray diffraction
1.8Å resolution

Crystal Structure of Gamma-Chymotrypsin in Complex with 7-Hydroxycoumarin

Released:
Source organism: Bos taurus
Primary publication:
Crystal structure of gamma-chymotrypsin in complex with 7-hydroxycoumarin.
J. Mol. Biol. 314 519-25 (2001)
PMID: 11846564

Function and Biology Details

Reaction catalysed:
Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.
Biochemical function:
Biological process:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chymotrypsinogen A Chain: 1
Molecule details ›
Chain: 1
Length: 245 amino acids
Theoretical weight: 25.69 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00766 (Residues: 1-245; Coverage: 100%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P42212
Unit cell:
a: 69.852Å b: 69.852Å c: 97.38Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.18 0.2