› 1k1b

X-ray diffraction
1.9Å resolution

Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family

Released:
DOI: 10.2210/pdb1k1b/pdb
PDB entry 1k1b coloured by chain, front view.
PDB entry 1k1b coloured by chain, side view.
PDB entry 1k1b coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family.
Michel F, Soler-Lopez M, Petosa C, Cramer P, Siebenlist U, Müller CW
EMBO J 20 6180-90 (2001)
PMID: 11707390

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149047 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
B-cell lymphoma 3 protein Chain: A
Molecule details ›
Chain: A
Length: 241 amino acids
Theoretical weight: 25.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P20749 (Residues: 127-367; Coverage: 53%)
Gene names: BCL3, BCL4, D19S37
Sequence domains: Ankyrin repeat
Structure domains: Ankyrin repeat-containing domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P21
Unit cell:
a: 31.35Å b: 50.907Å c: 59.495Å
α: 90° β: 102.04° γ: 90°
R-values:
R R work R free
0.179 0.177 0.217
Expression system: Escherichia coli

Quick links

Citations

9 review citations

The ankyrin repeat as molecular architecture for protein recognition.
Mosavi et al. (2004)
8 more

9 mentions without citation

A primer on ankyrin repeat function in TRP channels and beyond.
Gaudet R. (2008)
8 more