Articles - 1jzz mentioned but not cited (4)
- POPSCOMP: an automated interaction analysis of biomolecular complexes. Kleinjung J, Fraternali F. Nucleic Acids Res 33 W342-6 (2005)
- Conformational Sampling of Macrocyclic Drugs in Different Environments: Can We Find the Relevant Conformations? Poongavanam V, Danelius E, Peintner S, Alcaraz L, Caron G, Cummings MD, Wlodek S, Erdelyi M, Hawkins PCD, Ermondi G, Kihlberg J. ACS Omega 3 11742-11757 (2018)
- Structural signatures of antibiotic binding sites on the ribosome. David-Eden H, Mankin AS, Mandel-Gutfreund Y. Nucleic Acids Res 38 5982-5994 (2010)
- Ribosomal dynamics inferred from variations in experimental measurements. Gabashvili IS, Whirl-Carrillo M, Bada M, Banatao DR, Altman RB. RNA 9 1301-1307 (2003)
Reviews citing this publication (131)
- The exploration of macrocycles for drug discovery--an underexploited structural class. Driggers EM, Hale SP, Lee J, Terrett NK. Nat Rev Drug Discov 7 608-624 (2008)
- Ribosome structure and the mechanism of translation. Ramakrishnan V. Cell 108 557-572 (2002)
- Ribosome-targeting antibiotics and mechanisms of bacterial resistance. Wilson DN. Nat Rev Microbiol 12 35-48 (2014)
- Where will new antibiotics come from? Walsh C. Nat Rev Microbiol 1 65-70 (2003)
- Drugs, their targets and the nature and number of drug targets. Imming P, Sinning C, Meyer A. Nat Rev Drug Discov 5 821-834 (2006)
- Molecular basis of bacterial resistance to chloramphenicol and florfenicol. Schwarz S, Kehrenberg C, Doublet B, Cloeckaert A. FEMS Microbiol Rev 28 519-542 (2004)
- The bacterial ribosome as a target for antibiotics. Poehlsgaard J, Douthwaite S. Nat Rev Microbiol 3 870-881 (2005)
- The A-Z of bacterial translation inhibitors. Wilson DN. Crit Rev Biochem Mol Biol 44 393-433 (2009)
- Antibacterial natural products in medicinal chemistry--exodus or revival? von Nussbaum F, Brands M, Hinzen B, Weigand S, Häbich D. Angew Chem Int Ed Engl 45 5072-5129 (2006)
- How pathogenic bacteria evade mammalian sabotage in the battle for iron. Fischbach MA, Lin H, Liu DR, Walsh CT. Nat Chem Biol 2 132-138 (2006)
- Structural basis of the translational elongation cycle. Voorhees RM, Ramakrishnan V. Annu Rev Biochem 82 203-236 (2013)
- Analysis of RNA motifs. Leontis NB, Westhof E. Curr Opin Struct Biol 13 300-308 (2003)
- Molecular dynamics simulations of large macromolecular complexes. Perilla JR, Goh BC, Cassidy CK, Liu B, Bernardi RC, Rudack T, Yu H, Wu Z, Schulten K. Curr Opin Struct Biol 31 64-74 (2015)
- Regulatory nascent peptides in the ribosomal tunnel. Tenson T, Ehrenberg M. Cell 108 591-594 (2002)
- The weird and wonderful world of bacterial ribosome regulation. Wilson DN, Nierhaus KH. Crit Rev Biochem Mol Biol 42 187-219 (2007)
- A comprehensive review of glycosylated bacterial natural products. Elshahawi SI, Shaaban KA, Kharel MK, Thorson JS. Chem Soc Rev 44 7591-7697 (2015)
- RNA, the first macromolecular catalyst: the ribosome is a ribozyme. Steitz TA, Moore PB. Trends Biochem Sci 28 411-418 (2003)
- Antimicrobial resistance mechanisms among Campylobacter. Wieczorek K, Osek J. Biomed Res Int 2013 340605 (2013)
- Targeting RNA with small molecules. Tor Y. Chembiochem 4 998-1007 (2003)
- The macrolide antibiotic renaissance. Dinos GP. Br J Pharmacol 174 2967-2983 (2017)
- Ribosomal proteins in the spotlight. Wilson DN, Nierhaus KH. Crit Rev Biochem Mol Biol 40 243-267 (2005)
- Structure and Function of the Mitochondrial Ribosome. Greber BJ, Ban N. Annu Rev Biochem 85 103-132 (2016)
- Targeting Antibiotic Resistance. Chellat MF, Raguž L, Riedl R. Angew Chem Int Ed Engl 55 6600-6626 (2016)
- Antibiotics targeting ribosomes: resistance, selectivity, synergism and cellular regulation. Yonath A. Annu Rev Biochem 74 649-679 (2005)
- The oxazolidinones: past, present, and future. Shaw KJ, Barbachyn MR. Ann N Y Acad Sci 1241 48-70 (2011)
- Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design. Lin J, Zhou D, Steitz TA, Polikanov YS, Gagnon MG. Annu Rev Biochem 87 451-478 (2018)
- Malaria chemotherapeutics part I: History of antimalarial drug development, currently used therapeutics, and drugs in clinical development. Schlitzer M. ChemMedChem 2 944-986 (2007)
- Programmed drug-dependent ribosome stalling. Ramu H, Mankin A, Vazquez-Laslop N. Mol Microbiol 71 811-824 (2009)
- RNA as a drug target: the case of aminoglycosides. Vicens Q, Westhof E. Chembiochem 4 1018-1023 (2003)
- How Macrolide Antibiotics Work. Vázquez-Laslop N, Mankin AS. Trends Biochem Sci 43 668-684 (2018)
- Drugs targeting the ribosome. Hermann T. Curr Opin Struct Biol 15 355-366 (2005)
- The involvement of RNA in ribosome function. Moore PB, Steitz TA. Nature 418 229-235 (2002)
- Antibiotics and the ribosome. Tenson T, Mankin A. Mol Microbiol 59 1664-1677 (2006)
- The ketolides: a critical review. Zhanel GG, Walters M, Noreddin A, Vercaigne LM, Wierzbowski A, Embil JM, Gin AS, Douthwaite S, Hoban DJ. Drugs 62 1771-1804 (2002)
- The ribosomal peptidyl transferase center: structure, function, evolution, inhibition. Polacek N, Mankin AS. Crit Rev Biochem Mol Biol 40 285-311 (2005)
- The structural basis of large ribosomal subunit function. Moore PB, Steitz TA. Annu Rev Biochem 72 813-850 (2003)
- Glycosyltransferases: mechanisms and applications in natural product development. Liang DM, Liu JH, Wu H, Wang BB, Zhu HJ, Qiao JJ. Chem Soc Rev 44 8350-8374 (2015)
- Modulating splicing with small molecular inhibitors of the spliceosome. Effenberger KA, Urabe VK, Jurica MS. Wiley Interdiscip Rev RNA 8 (2017)
- Recent advances in isocyanide-based multicomponent chemistry. Dömling A. Curr Opin Chem Biol 6 306-313 (2002)
- Polyketide synthase and non-ribosomal peptide synthetase thioesterase selectivity: logic gate or a victim of fate? Horsman ME, Hari TP, Boddy CN. Nat Prod Rep 33 183-202 (2016)
- Antibiotics that target protein synthesis. McCoy LS, Xie Y, Tor Y. Wiley Interdiscip Rev RNA 2 209-232 (2011)
- How ribosomes make peptide bonds. Rodnina MV, Beringer M, Wintermeyer W. Trends Biochem Sci 32 20-26 (2007)
- Lincomycin, clindamycin and their applications. Spízek J, Rezanka T. Appl Microbiol Biotechnol 64 455-464 (2004)
- Structure-based discovery of antibacterial drugs. Simmons KJ, Chopra I, Fishwick CW. Nat Rev Microbiol 8 501-510 (2010)
- Role of natural product diversity in chemical biology. Hong J. Curr Opin Chem Biol 15 350-354 (2011)
- The social life of ribosomal proteins. Brodersen DE, Nissen P. FEBS J 272 2098-2108 (2005)
- Species-specific antibiotic-ribosome interactions: implications for drug development. Wilson DN, Harms JM, Nierhaus KH, Schlünzen F, Fucini P. Biol Chem 386 1239-1252 (2005)
- 5 S rRNA: structure and interactions. Szymański M, Barciszewska MZ, Erdmann VA, Barciszewski J. Biochem J 371 641-651 (2003)
- The genomic enzymology of antibiotic resistance. Morar M, Wright GD. Annu Rev Genet 44 25-51 (2010)
- Macrolide antibiotics in the ribosome exit tunnel: species-specific binding and action. Kannan K, Mankin AS. Ann N Y Acad Sci 1241 33-47 (2011)
- Rational ligand design for RNA: the role of static structure and conformational flexibility in target recognition. Hermann T. Biochimie 84 869-875 (2002)
- Avoidance of suicide in antibiotic-producing microbes. Cundliffe E, Demain AL. J Ind Microbiol Biotechnol 37 643-672 (2010)
- From Erythromycin to Azithromycin and New Potential Ribosome-Binding Antimicrobials. Jelić D, Antolović R. Antibiotics (Basel) 5 E29 (2016)
- Macrolide myths. Mankin AS. Curr Opin Microbiol 11 414-421 (2008)
- Three-way RNA junctions with remote tertiary contacts: a recurrent and highly versatile fold. de la Peña M, Dufour D, Gallego J. RNA 15 1949-1964 (2009)
- A brief history of antibiotics and select advances in their synthesis. Nicolaou KC, Rigol S. J Antibiot (Tokyo) 71 153-184 (2018)
- Improving on nature: antibiotics that target the ribosome. Sutcliffe JA. Curr Opin Microbiol 8 534-542 (2005)
- The tRNA Elbow in Structure, Recognition and Evolution. Zhang J, Ferré-D'Amaré AR. Life (Basel) 6 E3 (2016)
- Vancomycin resistance: occurrence, mechanisms and strategies to combat it. Boneca IG, Chiosis G. Expert Opin Ther Targets 7 311-328 (2003)
- Lincosamides: Chemical structure, biosynthesis, mechanism of action, resistance, and applications. Spížek J, Řezanka T. Biochem Pharmacol 133 20-28 (2017)
- Structure-based drug design meets the ribosome. Franceschi F, Duffy EM. Biochem Pharmacol 71 1016-1025 (2006)
- Chemical and functional diversity of small molecule ligands for RNA. Hermann T. Biopolymers 70 4-18 (2003)
- Recent developments in the identification of novel oxazolidinone antibacterial agents. Renslo AR, Luehr GW, Gordeev MF. Bioorg Med Chem 14 4227-4240 (2006)
- A structural view on the mechanism of the ribosome-catalyzed peptide bond formation. Simonović M, Steitz TA. Biochim Biophys Acta 1789 612-623 (2009)
- Molecular recognition of RNA: challenges for modelling interactions and plasticity. Fulle S, Gohlke H. J Mol Recognit 23 220-231 (2010)
- Chloramphenicol Derivatives as Antibacterial and Anticancer Agents: Historic Problems and Current Solutions. Dinos GP, Athanassopoulos CM, Missiri DA, Giannopoulou PC, Vlachogiannis IA, Papadopoulos GE, Papaioannou D, Kalpaxis DL. Antibiotics (Basel) 5 E20 (2016)
- Using Genome Sequence to Enable the Design of Medicines and Chemical Probes. Angelbello AJ, Chen JL, Childs-Disney JL, Zhang P, Wang ZF, Disney MD. Chem Rev 118 1599-1663 (2018)
- The search and its outcome: high-resolution structures of ribosomal particles from mesophilic, thermophilic, and halophilic bacteria at various functional states. Yonath A. Annu Rev Biophys Biomol Struct 31 257-273 (2002)
- Biological counterstrike: antibiotic resistance mechanisms of Gram-positive cocci. Woodford N. Clin Microbiol Infect 11 Suppl 3 2-21 (2005)
- On the specificity of antibiotics targeting the large ribosomal subunit. Wilson DN. Ann N Y Acad Sci 1241 1-16 (2011)
- The roles of RNA in the synthesis of protein. Moore PB, Steitz TA. Cold Spring Harb Perspect Biol 3 a003780 (2011)
- Ribosomal antibiotics: structural basis for resistance, synergism and selectivity. Auerbach T, Bashan A, Yonath A. Trends Biotechnol 22 570-576 (2004)
- Look and Outlook on Enzyme-Mediated Macrolide Resistance. Golkar T, Zieliński M, Berghuis AM. Front Microbiol 9 1942 (2018)
- Context-Specific Action of Ribosomal Antibiotics. Vázquez-Laslop N, Mankin AS. Annu Rev Microbiol 72 185-207 (2018)
- From peptide-bond formation to cotranslational folding: dynamic, regulatory and evolutionary aspects. Baram D, Yonath A. FEBS Lett 579 948-954 (2005)
- Ribosomal crystallography: initiation, peptide bond formation, and amino acid polymerization are hampered by antibiotics. Yonath A, Bashan A. Annu Rev Microbiol 58 233-251 (2004)
- Traffic jam at the bacterial sec translocase: targeting the SecA nanomotor by small-molecule inhibitors. Segers K, Anné J. Chem Biol 18 685-698 (2011)
- Ribosomal crystallography: a flexible nucleotide anchoring tRNA translocation, facilitates peptide-bond formation, chirality discrimination and antibiotics synergism. Agmon I, Amit M, Auerbach T, Bashan A, Baram D, Bartels H, Berisio R, Greenberg I, Harms J, Hansen HA, Kessler M, Pyetan E, Schluenzen F, Sittner A, Yonath A, Zarivach R. FEBS Lett 567 20-26 (2004)
- Ribosomal crystallography: peptide bond formation and its inhibition. Bashan A, Zarivach R, Schluenzen F, Agmon I, Harms J, Auerbach T, Baram D, Berisio R, Bartels H, Hansen HA, Fucini P, Wilson D, Peretz M, Kessler M, Yonath A. Biopolymers 70 19-41 (2003)
- After the ribosome structure: how does translocation work? Joseph S. RNA 9 160-164 (2003)
- Receptor-based screening assays for the detection of antibiotics residues - A review. Ahmed S, Ning J, Cheng G, Ahmad I, Li J, Mingyue L, Qu W, Iqbal M, Shabbir MAB, Yuan Z. Talanta 166 176-186 (2017)
- Speculative strategies for new antibacterials: all roads should not lead to Rome. Shapiro S. J Antibiot (Tokyo) 66 371-386 (2013)
- Single-molecule analysis of translational dynamics. Petrov A, Chen J, O'Leary S, Tsai A, Puglisi JD. Cold Spring Harb Perspect Biol 4 a011551 (2012)
- On the structural basis of peptide-bond formation and antibiotic resistance from atomic structures of the large ribosomal subunit. Steitz TA. FEBS Lett 579 955-958 (2005)
- Radical SAM enzymes in the biosynthesis of sugar-containing natural products. Ruszczycky MW, Ogasawara Y, Liu HW. Biochim Biophys Acta 1824 1231-1244 (2012)
- Regulation of antibiotic-resistance by non-coding RNAs in bacteria. Dar D, Sorek R. Curr Opin Microbiol 36 111-117 (2017)
- The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance. McCusker KP, Fujimori DG. ACS Chem Biol 7 64-72 (2012)
- Blackout in the powerhouse: clinical phenotypes associated with defects in the assembly of OXPHOS complexes and the mitoribosome. Hock DH, Robinson DRL, Stroud DA. Biochem J 477 4085-4132 (2020)
- Microbiological profile of a new topical antibacterial: retapamulin ointment 1%. Scangarella-Oman NE, Shawar RM, Bouchillon S, Hoban D. Expert Rev Anti Infect Ther 7 269-279 (2009)
- Antibiotics Resistance in Rhizobium: Type, Process, Mechanism and Benefit for Agriculture. Naamala J, Jaiswal SK, Dakora FD. Curr Microbiol 72 804-816 (2016)
- Can intracellular Staphylococcus aureus in osteomyelitis be treated using current antibiotics? A systematic review and narrative synthesis. Zelmer AR, Nelson R, Richter K, Atkins GJ. Bone Res 10 53 (2022)
- Elements of ribosomal drug resistance and specificity. Blaha GM, Polikanov YS, Steitz TA. Curr Opin Struct Biol 22 750-758 (2012)
- Ketolides: an emerging treatment for macrolide-resistant respiratory infections, focusing on S. pneumoniae. Zhanel GG, Hisanaga T, Nichol K, Wierzbowski A, Hoban DJ. Expert Opin Emerg Drugs 8 297-321 (2003)
- Ribosomal tolerance and peptide bond formation. Yonath A. Biol Chem 384 1411-1419 (2003)
- Which antibiotic for resistant Gram-positives, and why? Bradley JS. J Infect 68 Suppl 1 S63-75 (2014)
- ABC-F translation factors: from antibiotic resistance to immune response. Fostier CR, Monlezun L, Ousalem F, Singh S, Hunt JF, Boël G. FEBS Lett 595 675-706 (2021)
- Chiral Alkyl Halides: Underexplored Motifs in Medicine. Gál B, Bucher C, Burns NZ. Mar Drugs 14 E206 (2016)
- Evaluation of macrolides for possible use against multidrug-resistant Mycobacterium tuberculosis. van der Paardt AF, Wilffert B, Akkerman OW, de Lange WC, van Soolingen D, Sinha B, van der Werf TS, Kosterink JG, Alffenaar JW. Eur Respir J 46 444-455 (2015)
- A Bright Future for Antibiotics? Matzov D, Bashan A, Yonath A. Annu Rev Biochem 86 567-583 (2017)
- Frontiers and opportunities in chemoenzymatic synthesis. Mortison JD, Sherman DH. J Org Chem 75 7041-7051 (2010)
- Biological implications of the ribosome's stunning stereochemistry. Zimmerman E, Yonath A. Chembiochem 10 63-72 (2009)
- Intraribosomal regulation of expression and fate of proteins. Nakatogawa H, Ito K. Chembiochem 5 48-51 (2004)
- Ribosome biogenesis in disease: new players and therapeutic targets. Jiao L, Liu Y, Yu XY, Pan X, Zhang Y, Tu J, Song YH, Li Y. Signal Transduct Target Ther 8 15 (2023)
- Targeted antibiotic discovery through biosynthesis-associated resistance determinants: target directed genome mining. O'Neill EC, Schorn M, Larson CB, Millán-Aguiñaga N. Crit Rev Microbiol 45 255-277 (2019)
- Desquamative inflammatory vaginitis. Reichman O, Sobel J. Best Pract Res Clin Obstet Gynaecol 28 1042-1050 (2014)
- Revisiting Antibiotic Resistance: Mechanistic Foundations to Evolutionary Outlook. Hasan CM, Dutta D, Nguyen ANT. Antibiotics (Basel) 11 40 (2021)
- Ribosome's mode of function: myths, facts and recent results. Wekselman I, Davidovich C, Agmon I, Zimmerman E, Rozenberg H, Bashan A, Berisio R, Yonath A. J Pept Sci 15 122-130 (2009)
- Polyketide stereocontrol: a study in chemical biology. Weissman KJ. Beilstein J Org Chem 13 348-371 (2017)
- Halogenase engineering and its utility in medicinal chemistry. Fraley AE, Sherman DH. Bioorg Med Chem Lett 28 1992-1999 (2018)
- Structure-based organic synthesis of drug prototypes: a personal odyssey. Hanessian S. ChemMedChem 1 1301-1330 (2006)
- Azithromycin through the Lens of the COVID-19 Treatment. Kournoutou GG, Dinos G. Antibiotics (Basel) 11 1063 (2022)
- Structural insight into functional aspects of ribosomal RNA targeting. Yonath A. Chembiochem 4 1008-1017 (2003)
- Advanced Methods for Studying Structure and Interactions of Macrolide Antibiotics. Jednačak T, Mikulandra I, Novak P. Int J Mol Sci 21 E7799 (2020)
- Biosynthesis and incorporation of an alkylproline-derivative (APD) precursor into complex natural products. Janata J, Kamenik Z, Gazak R, Kadlcik S, Najmanova L. Nat Prod Rep 35 257-289 (2018)
- Ribosomal Antibiotics: Contemporary Challenges. Auerbach-Nevo T, Baram D, Bashan A, Belousoff M, Breiner E, Davidovich C, Cimicata G, Eyal Z, Halfon Y, Krupkin M, Matzov D, Metz M, Rufayda M, Peretz M, Pick O, Pyetan E, Rozenberg H, Shalev-Benami M, Wekselman I, Zarivach R, Zimmerman E, Assis N, Bloch J, Israeli H, Kalaora R, Lim L, Sade-Falk O, Shapira T, Taha-Salaime L, Tang H, Yonath A. Antibiotics (Basel) 5 E24 (2016)
- Ribosomal tunnel and translation regulation. Bogdanov AA, Sumbatyan NV, Shishkina AV, Karpenko VV, Korshunova GA. Biochemistry (Mosc) 75 1501-1516 (2010)
- Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond. Repac Antić D, Parčina M, Gobin I, Petković Didović M. Antibiotics (Basel) 11 1105 (2022)
- Exploring the mechanism of protein synthesis with modified substrates and novel intermediate mimics. Weinger JS, Strobel SA. Blood Cells Mol Dis 38 110-116 (2007)
- Ribosome Protection Proteins-"New" Players in the Global Arms Race with Antibiotic-Resistant Pathogens. Ero R, Yan XF, Gao YG. Int J Mol Sci 22 5356 (2021)
- Enzymatic noncovalent synthesis of peptide assemblies generates multimolecular crowding in cells for biomedical applications. Yi M, Tan W, Guo J, Xu B. Chem Commun (Camb) 57 12870-12879 (2021)
- Insights into functional modulation of catalytic RNA activity. Vourekas A, Stamatopoulou V, Toumpeki C, Tsitlaidou M, Drainas D. IUBMB Life 60 669-683 (2008)
- Ribosome-Directed Therapies in Cancer. Temaj G, Chichiarelli S, Eufemi M, Altieri F, Hadziselimovic R, Farooqi AA, Yaylim I, Saso L. Biomedicines 10 2088 (2022)
- The design of novel classes of macrolides for neutrophil-dominated inflammatory diseases. Eraković Haber V, Bosnar M, Kragol G. Future Med Chem 6 657-674 (2014)
- Aminoglycoside interactions with RNAs and nucleases. Kirsebom LA, Virtanen A, Mikkelsen NE. Handb Exp Pharmacol 73-96 (2006)
- Insight into the functional versatility of RNA through model-making with applications to data fitting. Bevilacqua PC, Cerrone-Szakal AL, Siegfried NA. Q Rev Biophys 40 55-85 (2007)
- Ribosome-targeting antibiotics and resistance via ribosomal RNA methylation. Jeremia L, Deprez BE, Dey D, Conn GL, Wuest WM. RSC Med Chem 14 624-643 (2023)
- Introduction of a nitrogen-containing side chain appended on C-10 of cethromycin leads to reduced CYP3A4 inhibition (WO2014049356A1). Liang JH. Expert Opin Ther Pat 25 119-123 (2015)
- Moving Past the Routine Use of Macrolides-Reviewing the Role of Combination Therapy in Community-Acquired Pneumonia. Shumilak G, Sligl WI. Curr Infect Dis Rep 20 45 (2018)
- Structural biology: a high-tech tool for biomedical research. Machius M. Curr Opin Nephrol Hypertens 12 431-438 (2003)
- The role of adjuvants in overcoming antibacterial resistance due to enzymatic drug modification. El-Khoury C, Mansour E, Yuliandra Y, Lai F, Hawkins BA, Du JJ, Sundberg EJ, Sluis-Cremer N, Hibbs DE, Groundwater PW. RSC Med Chem 13 1276-1299 (2022)
- [Assembly of ribonucleoparticle complexes]. Hugo N, Bouvet P. Med Sci (Paris) 19 1271-1279 (2003)
Articles citing this publication (439)
- High resolution structure of the large ribosomal subunit from a mesophilic eubacterium. Harms J, Schluenzen F, Zarivach R, Bashan A, Gat S, Agmon I, Bartels H, Franceschi F, Yonath A. Cell 107 679-688 (2001)
- The non-Watson-Crick base pairs and their associated isostericity matrices. Leontis NB, Stombaugh J, Westhof E. Nucleic Acids Res 30 3497-3531 (2002)
- The Cfr rRNA methyltransferase confers resistance to Phenicols, Lincosamides, Oxazolidinones, Pleuromutilins, and Streptogramin A antibiotics. Long KS, Poehlsgaard J, Kehrenberg C, Schwarz S, Vester B. Antimicrob Agents Chemother 50 2500-2505 (2006)
- The structures of four macrolide antibiotics bound to the large ribosomal subunit. Hansen JL, Ippolito JA, Ban N, Nissen P, Moore PB, Steitz TA. Mol Cell 10 117-128 (2002)
- The roles of ribosomal proteins in the structure assembly, and evolution of the large ribosomal subunit. Klein DJ, Moore PB, Steitz TA. J Mol Biol 340 141-177 (2004)
- Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance. Tu D, Blaha G, Moore PB, Steitz TA. Cell 121 257-270 (2005)
- Letter Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Serganov A, Polonskaia A, Phan AT, Breaker RR, Patel DJ. Nature 441 1167-1171 (2006)
- Nascent membrane and secretory proteins differ in FRET-detected folding far inside the ribosome and in their exposure to ribosomal proteins. Woolhead CA, McCormick PJ, Johnson AE. Cell 116 725-736 (2004)
- Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Dunkle JA, Xiong L, Mankin AS, Cate JH. Proc Natl Acad Sci U S A 107 17152-17157 (2010)
- Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit. Hansen JL, Moore PB, Steitz TA. J Mol Biol 330 1061-1075 (2003)
- Real-time tRNA transit on single translating ribosomes at codon resolution. Uemura S, Aitken CE, Korlach J, Flusberg BA, Turner SW, Puglisi JD. Nature 464 1012-1017 (2010)
- Acquisition of a natural resistance gene renders a clinical strain of methicillin-resistant Staphylococcus aureus resistant to the synthetic antibiotic linezolid. Toh SM, Xiong L, Arias CA, Villegas MV, Lolans K, Quinn J, Mankin AS. Mol Microbiol 64 1506-1514 (2007)
- The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. Tenson T, Lovmar M, Ehrenberg M. J Mol Biol 330 1005-1014 (2003)
- A new mechanism for chloramphenicol, florfenicol and clindamycin resistance: methylation of 23S ribosomal RNA at A2503. Kehrenberg C, Schwarz S, Jacobsen L, Hansen LH, Vester B. Mol Microbiol 57 1064-1073 (2005)
- Molecular mechanism of drug-dependent ribosome stalling. Vazquez-Laslop N, Thum C, Mankin AS. Mol Cell 30 190-202 (2008)
- Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin. Harms JM, Wilson DN, Schluenzen F, Connell SR, Stachelhaus T, Zaborowska Z, Spahn CM, Fucini P. Mol Cell 30 26-38 (2008)
- The ribosome as an entropy trap. Sievers A, Beringer M, Rodnina MV, Wolfenden R. Proc Natl Acad Sci U S A 101 7897-7901 (2004)
- Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression. Bashan A, Agmon I, Zarivach R, Schluenzen F, Harms J, Berisio R, Bartels H, Franceschi F, Auerbach T, Hansen HA, Kossoy E, Kessler M, Yonath A. Mol Cell 11 91-102 (2003)
- The complete structure of the large subunit of the mammalian mitochondrial ribosome. Greber BJ, Boehringer D, Leibundgut M, Bieri P, Leitner A, Schmitz N, Aebersold R, Ban N. Nature 515 283-286 (2014)
- The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning. Wilson DN, Schluenzen F, Harms JM, Starosta AL, Connell SR, Fucini P. Proc Natl Acad Sci U S A 105 13339-13344 (2008)
- Revisiting the structures of several antibiotics bound to the bacterial ribosome. Bulkley D, Innis CA, Blaha G, Steitz TA. Proc Natl Acad Sci U S A 107 17158-17163 (2010)
- Structural basis for the antibiotic activity of ketolides and azalides. Schlünzen F, Harms JM, Franceschi F, Hansen HA, Bartels H, Zarivach R, Yonath A. Structure 11 329-338 (2003)
- The site of action of oxazolidinone antibiotics in living bacteria and in human mitochondria. Leach KL, Swaney SM, Colca JR, McDonald WG, Blinn JR, Thomasco LM, Gadwood RC, Shinabarger D, Xiong L, Mankin AS. Mol Cell 26 393-402 (2007)
- Resistance to macrolides and related antibiotics in Streptococcus pneumoniae. Leclercq R, Courvalin P. Antimicrob Agents Chemother 46 2727-2734 (2002)
- Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin. Schlünzen F, Pyetan E, Fucini P, Yonath A, Harms JM. Mol Microbiol 54 1287-1294 (2004)
- Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2'-O-methylations in 16S and 23S rRNAs. Johansen SK, Maus CE, Plikaytis BB, Douthwaite S. Mol Cell 23 173-182 (2006)
- Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700). Locke JB, Hilgers M, Shaw KJ. Antimicrob Agents Chemother 53 5265-5274 (2009)
- Structural insight into the role of the ribosomal tunnel in cellular regulation. Berisio R, Schluenzen F, Harms J, Bashan A, Auerbach T, Baram D, Yonath A. Nat Struct Biol 10 366-370 (2003)
- An unbiased cDNA library prepared from isolated Aplysia sensory neuron processes is enriched for cytoskeletal and translational mRNAs. Moccia R, Chen D, Lyles V, Kapuya E, E Y, Kalachikov S, Spahn CM, Frank J, Kandel ER, Barad M, Martin KC. J Neurosci 23 9409-9417 (2003)
- Bacterial programmed cell death systems as targets for antibiotics. Engelberg-Kulka H, Sat B, Reches M, Amitai S, Hazan R. Trends Microbiol 12 66-71 (2004)
- U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome. Gürel G, Blaha G, Moore PB, Steitz TA. J Mol Biol 389 146-156 (2009)
- Detection of macrolide resistance in Mycoplasma pneumoniae by real-time PCR and high-resolution melt analysis. Wolff BJ, Thacker WL, Schwartz SB, Winchell JM. Antimicrob Agents Chemother 52 3542-3549 (2008)
- The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results. Rosenbaum G, Alkire RW, Evans G, Rotella FJ, Lazarski K, Zhang RG, Ginell SL, Duke N, Naday I, Lazarz J, Molitsky MJ, Keefe L, Gonczy J, Rock L, Sanishvili R, Walsh MA, Westbrook E, Joachimiak A. J Synchrotron Radiat 13 30-45 (2006)
- Precise small-molecule recognition of a toxic CUG RNA repeat expansion. Rzuczek SG, Colgan LA, Nakai Y, Cameron MD, Furling D, Yasuda R, Disney MD. Nat Chem Biol 13 188-193 (2017)
- Structural insight into the antibiotic action of telithromycin against resistant mutants. Berisio R, Harms J, Schluenzen F, Zarivach R, Hansen HA, Fucini P, Yonath A. J Bacteriol 185 4276-4279 (2003)
- The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide. Vázquez-Laslop N, Ramu H, Klepacki D, Kannan K, Mankin AS. EMBO J 29 3108-3117 (2010)
- Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria. Giessing AM, Jensen SS, Rasmussen A, Hansen LH, Gondela A, Long K, Vester B, Kirpekar F. RNA 15 327-336 (2009)
- Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA A site oligonucleotide. Vicens Q, Westhof E. J Mol Biol 326 1175-1188 (2003)
- The methyltransferase YfgB/RlmN is responsible for modification of adenosine 2503 in 23S rRNA. Toh SM, Xiong L, Bae T, Mankin AS. RNA 14 98-106 (2008)
- Transcriptional regulation and signature patterns revealed by microarray analyses of Streptococcus pneumoniae R6 challenged with sublethal concentrations of translation inhibitors. Ng WL, Kazmierczak KM, Robertson GT, Gilmour R, Winkler ME. J Bacteriol 185 359-370 (2003)
- Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin. Harms JM, Schlünzen F, Fucini P, Bartels H, Yonath A. BMC Biol 2 4 (2004)
- Selective protein synthesis by ribosomes with a drug-obstructed exit tunnel. Kannan K, Vázquez-Laslop N, Mankin AS. Cell 151 508-520 (2012)
- The general mode of translation inhibition by macrolide antibiotics. Kannan K, Kanabar P, Schryer D, Florin T, Oh E, Bahroos N, Tenson T, Weissman JS, Mankin AS. Proc Natl Acad Sci U S A 111 15958-15963 (2014)
- The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae. Sherman DH, Li S, Yermalitskaya LV, Kim Y, Smith JA, Waterman MR, Podust LM. J Biol Chem 281 26289-26297 (2006)
- Global transcriptional response of Bacillus subtilis to treatment with subinhibitory concentrations of antibiotics that inhibit protein synthesis. Lin JT, Connelly MB, Amolo C, Otani S, Yaver DS. Antimicrob Agents Chemother 49 1915-1926 (2005)
- Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. Smith LK, Mankin AS. Antimicrob Agents Chemother 52 1703-1712 (2008)
- RNA structure comparison, motif search and discovery using a reduced representation of RNA conformational space. Duarte CM, Wadley LM, Pyle AM. Nucleic Acids Res 31 4755-4761 (2003)
- Context-specific inhibition of translation by ribosomal antibiotics targeting the peptidyl transferase center. Marks J, Kannan K, Roncase EJ, Klepacki D, Kefi A, Orelle C, Vázquez-Laslop N, Mankin AS. Proc Natl Acad Sci U S A 113 12150-12155 (2016)
- In vitro selection and characterization of resistance to macrolides and related antibiotics in Mycoplasma pneumoniae. Pereyre S, Guyot C, Renaudin H, Charron A, Bébéar C, Bébéar CM. Antimicrob Agents Chemother 48 460-465 (2004)
- Nascent peptide in the ribosome exit tunnel affects functional properties of the A-site of the peptidyl transferase center. Ramu H, Vázquez-Laslop N, Klepacki D, Dai Q, Piccirilli J, Micura R, Mankin AS. Mol Cell 41 321-330 (2011)
- The critical role of the universally conserved A2602 of 23S ribosomal RNA in the release of the nascent peptide during translation termination. Polacek N, Gomez MJ, Ito K, Xiong L, Nakamura Y, Mankin A. Mol Cell 11 103-112 (2003)
- Sequence analysis of twin ATP binding cassette proteins involved in translational control, antibiotic resistance, and ribonuclease L inhibition. Kerr ID. Biochem Biophys Res Commun 315 166-173 (2004)
- X-ray crystallography study on ribosome recycling: the mechanism of binding and action of RRF on the 50S ribosomal subunit. Wilson DN, Schluenzen F, Harms JM, Yoshida T, Ohkubo T, Albrecht R, Buerger J, Kobayashi Y, Fucini P. EMBO J 24 251-260 (2005)
- Mutations in ribosomal protein L3 and 23S ribosomal RNA at the peptidyl transferase centre are associated with reduced susceptibility to tiamulin in Brachyspira spp. isolates. Pringle M, Poehlsgaard J, Vester B, Long KS. Mol Microbiol 54 1295-1306 (2004)
- Following the intersubunit conformation of the ribosome during translation in real time. Aitken CE, Puglisi JD. Nat Struct Mol Biol 17 793-800 (2010)
- Size, shape, and flexibility of RNA structures. Hyeon C, Dima RI, Thirumalai D. J Chem Phys 125 194905 (2006)
- Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus. Eyal Z, Matzov D, Krupkin M, Wekselman I, Paukner S, Zimmerman E, Rozenberg H, Bashan A, Yonath A. Proc Natl Acad Sci U S A 112 E5805-14 (2015)
- Dual effects of MLS antibiotics: transcriptional modulation and interactions on the ribosome. Tsui WH, Yim G, Wang HH, McClure JE, Surette MG, Davies J. Chem Biol 11 1307-1316 (2004)
- Macrolide resistance by ribosomal mutation in clinical isolates of Streptococcus pneumoniae from the PROTEKT 1999-2000 study. Farrell DJ, Douthwaite S, Morrissey I, Bakker S, Poehlsgaard J, Jakobsen L, Felmingham D. Antimicrob Agents Chemother 47 1777-1783 (2003)
- Molecular basis of intrinsic macrolide resistance in clinical isolates of Mycobacterium fortuitum. Nash KA, Zhang Y, Brown-Elliott BA, Wallace RJ. J Antimicrob Chemother 55 170-177 (2005)
- Structure-activity relationships of diverse oxazolidinones for linezolid-resistant Staphylococcus aureus strains possessing the cfr methyltransferase gene or ribosomal mutations. Locke JB, Finn J, Hilgers M, Morales G, Rahawi S, G C K, Picazo JJ, Im W, Shaw KJ, Stein JL. Antimicrob Agents Chemother 54 5337-5343 (2010)
- Three-dimensional structures of translating ribosomes by Cryo-EM. Gilbert RJ, Fucini P, Connell S, Fuller SD, Nierhaus KH, Robinson CV, Dobson CM, Stuart DI. Mol Cell 14 57-66 (2004)
- Mutations in 23S rRNA account for intrinsic resistance to macrolides in Mycoplasma hominis and Mycoplasma fermentans and for acquired resistance to macrolides in M. hominis. Pereyre S, Gonzalez P, De Barbeyrac B, Darnige A, Renaudin H, Charron A, Raherison S, Bébéar C, Bébéar CM. Antimicrob Agents Chemother 46 3142-3150 (2002)
- Genome sequencing of linezolid-resistant Streptococcus pneumoniae mutants reveals novel mechanisms of resistance. Feng J, Lupien A, Gingras H, Wasserscheid J, Dewar K, Légaré D, Ouellette M. Genome Res 19 1214-1223 (2009)
- Distribution of the multidrug resistance gene cfr in Staphylococcus species isolates from swine farms in China. Wang Y, Zhang W, Wang J, Wu C, Shen Z, Fu X, Yan Y, Zhang Q, Schwarz S, Shen J. Antimicrob Agents Chemother 56 1485-1490 (2012)
- Resistance to the macrolide antibiotic tylosin is conferred by single methylations at 23S rRNA nucleotides G748 and A2058 acting in synergy. Liu M, Douthwaite S. Proc Natl Acad Sci U S A 99 14658-14663 (2002)
- Macrolide antibiotics allosterically predispose the ribosome for translation arrest. Sothiselvam S, Liu B, Han W, Ramu H, Klepacki D, Atkinson GC, Brauer A, Remm M, Tenson T, Schulten K, Vázquez-Laslop N, Mankin AS. Proc Natl Acad Sci U S A 111 9804-9809 (2014)
- Novel mutations in ribosomal proteins L4 and L22 that confer erythromycin resistance in Escherichia coli. Zaman S, Fitzpatrick M, Lindahl L, Zengel J. Mol Microbiol 66 1039-1050 (2007)
- Oxazolidinones inhibit cellular proliferation via inhibition of mitochondrial protein synthesis. Nagiec EE, Wu L, Swaney SM, Chosay JG, Ross DE, Brieland JK, Leach KL. Antimicrob Agents Chemother 49 3896-3902 (2005)
- Does linezolid cause lactic acidosis by inhibiting mitochondrial protein synthesis? Palenzuela L, Hahn NM, Nelson RP, Arno JN, Schobert C, Bethel R, Ostrowski LA, Sharma MR, Datta PP, Agrawal RK, Schwartz JE, Hirano M. Clin Infect Dis 40 e113-6 (2005)
- Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry. Madsen CT, Mengel-Jørgensen J, Kirpekar F, Douthwaite S. Nucleic Acids Res 31 4738-4746 (2003)
- Activity of the ketolide telithromycin is refractory to Erm monomethylation of bacterial rRNA. Liu M, Douthwaite S. Antimicrob Agents Chemother 46 1629-1633 (2002)
- Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A. Polikanov YS, Starosta AL, Juette MF, Altman RB, Terry DS, Lu W, Burnett BJ, Dinos G, Reynolds KA, Blanchard SC, Steitz TA, Wilson DN. Mol Cell 58 832-844 (2015)
- RNA methylation by radical SAM enzymes RlmN and Cfr proceeds via methylene transfer and hydride shift. Yan F, Fujimori DG. Proc Natl Acad Sci U S A 108 3930-3934 (2011)
- Selective oxidation of carbolide C-H bonds by an engineered macrolide P450 mono-oxygenase. Li S, Chaulagain MR, Knauff AR, Podust LM, Montgomery J, Sherman DH. Proc Natl Acad Sci U S A 106 18463-18468 (2009)
- The protein synthesis inhibitors, oxazolidinones and chloramphenicol, cause extensive translational inaccuracy in vivo. Thompson J, O'Connor M, Mills JA, Dahlberg AE. J Mol Biol 322 273-279 (2002)
- The structural basis of macrolide-ribosome binding assessed using mutagenesis of 23S rRNA positions 2058 and 2059. Pfister P, Jenni S, Poehlsgaard J, Thomas A, Douthwaite S, Ban N, Böttger EC. J Mol Biol 342 1569-1581 (2004)
- The binding mode of the trigger factor on the ribosome: implications for protein folding and SRP interaction. Schlünzen F, Wilson DN, Tian P, Harms JM, McInnes SJ, Hansen HA, Albrecht R, Buerger J, Wilbanks SM, Fucini P. Structure 13 1685-1694 (2005)
- Induction of erm(C) expression by noninducing antibiotics. Bailey M, Chettiath T, Mankin AS. Antimicrob Agents Chemother 52 866-874 (2008)
- Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. Blaha G, Gürel G, Schroeder SJ, Moore PB, Steitz TA. J Mol Biol 379 505-519 (2008)
- Mutations in a 23S rRNA gene of Chlamydia trachomatis associated with resistance to macrolides. Misyurina OY, Chipitsyna EV, Finashutina YP, Lazarev VN, Akopian TA, Savicheva AM, Govorun VM. Antimicrob Agents Chemother 48 1347-1349 (2004)
- Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model. Angelbello AJ, Rzuczek SG, Mckee KK, Chen JL, Olafson H, Cameron MD, Moss WN, Wang ET, Disney MD. Proc Natl Acad Sci U S A 116 7799-7804 (2019)
- Antibiotic susceptibility of mammalian mitochondrial translation. Zhang L, Ging NC, Komoda T, Hanada T, Suzuki T, Watanabe K. FEBS Lett 579 6423-6427 (2005)
- Ribosomal and non-ribosomal resistance to oxazolidinones: species-specific idiosyncrasy of ribosomal alterations. Sander P, Belova L, Kidan YG, Pfister P, Mankin AS, Böttger EC. Mol Microbiol 46 1295-1304 (2002)
- Interplay between the ribosomal tunnel, nascent chain, and macrolides influences drug inhibition. Starosta AL, Karpenko VV, Shishkina AV, Mikolajka A, Sumbatyan NV, Schluenzen F, Korshunova GA, Bogdanov AA, Wilson DN. Chem Biol 17 504-514 (2010)
- Effect of Veillonella parvula on the antimicrobial resistance and gene expression of Streptococcus mutans grown in a dual-species biofilm. Luppens SB, Kara D, Bandounas L, Jonker MJ, Wittink FR, Bruning O, Breit TM, Ten Cate JM, Crielaard W. Oral Microbiol Immunol 23 183-189 (2008)
- Structure of the chloroplast ribosome: novel domains for translation regulation. Manuell AL, Quispe J, Mayfield SP. PLoS Biol 5 e209 (2007)
- 23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A-->G. Pfister P, Corti N, Hobbie S, Bruell C, Zarivach R, Yonath A, Böttger EC. Proc Natl Acad Sci U S A 102 5180-5185 (2005)
- Chloramphenicol biosynthesis: the structure of CmlS, a flavin-dependent halogenase showing a covalent flavin-aspartate bond. Podzelinska K, Latimer R, Bhattacharya A, Vining LC, Zechel DL, Jia Z. J Mol Biol 397 316-331 (2010)
- RMF inactivates ribosomes by covering the peptidyl transferase centre and entrance of peptide exit tunnel. Yoshida H, Yamamoto H, Uchiumi T, Wada A. Genes Cells 9 271-278 (2004)
- The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel. Sergiev PV, Serebryakova MV, Bogdanov AA, Dontsova OA. J Mol Biol 375 291-300 (2008)
- Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae. Ward SL, Hu Z, Schirmer A, Reid R, Revill WP, Reeves CD, Petrakovsky OV, Dong SD, Katz L. Antimicrob Agents Chemother 48 4703-4712 (2004)
- Comprehensive identification of translation start sites by tetracycline-inhibited ribosome profiling. Nakahigashi K, Takai Y, Kimura M, Abe N, Nakayashiki T, Shiwa Y, Yoshikawa H, Wanner BL, Ishihama Y, Mori H. DNA Res 23 193-201 (2016)
- Effect of subtherapeutic vs. therapeutic administration of macrolides on antimicrobial resistance in Mannheimia haemolytica and enterococci isolated from beef cattle. Zaheer R, Cook SR, Klima CL, Stanford K, Alexander T, Topp E, Read RR, McAllister TA. Front Microbiol 4 133 (2013)
- FRET enabled real time detection of RNA-small molecule binding. Xie Y, Dix AV, Tor Y. J Am Chem Soc 131 17605-17614 (2009)
- Structure and mechanism of the lincosamide antibiotic adenylyltransferase LinB. Morar M, Bhullar K, Hughes DW, Junop M, Wright GD. Structure 17 1649-1659 (2009)
- A novel phenicol exporter gene, fexB, found in enterococci of animal origin. Liu H, Wang Y, Wu C, Schwarz S, Shen Z, Jeon B, Ding S, Zhang Q, Shen J. J Antimicrob Chemother 67 322-325 (2012)
- Erythromycin- and chloramphenicol-induced ribosomal assembly defects are secondary effects of protein synthesis inhibition. Siibak T, Peil L, Xiong L, Mankin A, Remme J, Tenson T. Antimicrob Agents Chemother 53 563-571 (2009)
- Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites. Dharia NV, Plouffe D, Bopp SE, González-Páez GE, Lucas C, Salas C, Soberon V, Bursulaya B, Kochel TJ, Bacon DJ, Winzeler EA. Genome Res 20 1534-1544 (2010)
- Mechanisms of resistance to chloramphenicol in Pseudomonas putida KT2440. Fernández M, Conde S, de la Torre J, Molina-Santiago C, Ramos JL, Duque E. Antimicrob Agents Chemother 56 1001-1009 (2012)
- Panel of Bacillus subtilis reporter strains indicative of various modes of action. Hutter B, Fischer C, Jacobi A, Schaab C, Loferer H. Antimicrob Agents Chemother 48 2588-2594 (2004)
- R chi-01, a new family of oxazolidinones that overcome ribosome-based linezolid resistance. Skripkin E, McConnell TS, DeVito J, Lawrence L, Ippolito JA, Duffy EM, Sutcliffe J, Franceschi F. Antimicrob Agents Chemother 52 3550-3557 (2008)
- Role of antibiotic ligand in nascent peptide-dependent ribosome stalling. Vázquez-Laslop N, Klepacki D, Mulhearn DC, Ramu H, Krasnykh O, Franzblau S, Mankin AS. Proc Natl Acad Sci U S A 108 10496-10501 (2011)
- Characterization of the Bacillus subtilis GTPase YloQ and its role in ribosome function. Campbell TL, Daigle DM, Brown ED. Biochem J 389 843-852 (2005)
- Three-dimensional motifs from the SCOR, structural classification of RNA database: extruded strands, base triples, tetraloops and U-turns. Klosterman PS, Hendrix DK, Tamura M, Holbrook SR, Brenner SE. Nucleic Acids Res 32 2342-2352 (2004)
- Frequency of development and associated physiological cost of azithromycin resistance in Chlamydia psittaci 6BC and C. trachomatis L2. Binet R, Maurelli AT. Antimicrob Agents Chemother 51 4267-4275 (2007)
- Macrolides selectively inhibit mutant KCNJ5 potassium channels that cause aldosterone-producing adenoma. Scholl UI, Abriola L, Zhang C, Reimer EN, Plummer M, Kazmierczak BI, Zhang J, Hoyer D, Merkel JS, Wang W, Lifton RP. J Clin Invest 127 2739-2750 (2017)
- Recombineering reveals a diverse collection of ribosomal proteins L4 and L22 that confer resistance to macrolide antibiotics. Diner EJ, Hayes CS. J Mol Biol 386 300-315 (2009)
- Binding site of the bridged macrolides in the Escherichia coli ribosome. Xiong L, Korkhin Y, Mankin AS. Antimicrob Agents Chemother 49 281-288 (2005)
- Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum. Wilson DW, Goodman CD, Sleebs BE, Weiss GE, de Jong NW, Angrisano F, Langer C, Baum J, Crabb BS, Gilson PR, McFadden GI, Beeson JG. BMC Biol 13 52 (2015)
- Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics in Mycobacterium smegmatis by perturbation of the drug binding pocket. Long KS, Poehlsgaard J, Hansen LH, Hobbie SN, Böttger EC, Vester B. Mol Microbiol 71 1218-1227 (2009)
- The many paths to frameshifting: kinetic modelling and analysis of the effects of different elongation steps on programmed -1 ribosomal frameshifting. Liao PY, Choi YS, Dinman JD, Lee KH. Nucleic Acids Res 39 300-312 (2011)
- Characterization and mechanistic studies of DesII: a radical S-adenosyl-L-methionine enzyme involved in the biosynthesis of TDP-D-desosamine. Szu PH, Ruszczycky MW, Choi SH, Yan F, Liu HW. J Am Chem Soc 131 14030-14042 (2009)
- Lecture On peptide bond formation, translocation, nascent protein progression and the regulatory properties of ribosomes. Derived on 20 October 2002 at the 28th FEBS Meeting in Istanbul. Agmon I, Auerbach T, Baram D, Bartels H, Bashan A, Berisio R, Fucini P, Hansen HA, Harms J, Kessler M, Peretz M, Schluenzen F, Yonath A, Zarivach R. Eur J Biochem 270 2543-2556 (2003)
- Rational Design of Small Molecules Targeting Oncogenic Noncoding RNAs from Sequence. Disney MD, Angelbello AJ. Acc Chem Res 49 2698-2704 (2016)
- Biochemical characterization of the interactions of the novel pleuromutilin derivative retapamulin with bacterial ribosomes. Yan K, Madden L, Choudhry AE, Voigt CS, Copeland RA, Gontarek RR. Antimicrob Agents Chemother 50 3875-3881 (2006)
- Modifications in Thermus thermophilus 23 S ribosomal RNA are centered in regions of RNA-RNA contact. Mengel-Jørgensen J, Jensen SS, Rasmussen A, Poehlsgaard J, Iversen JJL, Kirpekar F. J Biol Chem 281 22108-22117 (2006)
- Oral administration of erythromycin decreases RNA toxicity in myotonic dystrophy. Nakamori M, Taylor K, Mochizuki H, Sobczak K, Takahashi MP. Ann Clin Transl Neurol 3 42-54 (2016)
- Statics of the ribosomal exit tunnel: implications for cotranslational peptide folding, elongation regulation, and antibiotics binding. Fulle S, Gohlke H. J Mol Biol 387 502-517 (2009)
- High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition. Svetlov MS, Plessa E, Chen CW, Bougas A, Krokidis MG, Dinos GP, Polikanov YS. RNA 25 600-606 (2019)
- Polyene antibiotic that inhibits membrane transport proteins. te Welscher YM, van Leeuwen MR, de Kruijff B, Dijksterhuis J, Breukink E. Proc Natl Acad Sci U S A 109 11156-11159 (2012)
- Structure of the base of the L7/L12 stalk of the Haloarcula marismortui large ribosomal subunit: analysis of L11 movements. Kavran JM, Steitz TA. J Mol Biol 371 1047-1059 (2007)
- Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. Belousoff MJ, Shapira T, Bashan A, Zimmerman E, Rozenberg H, Arakawa K, Kinashi H, Yonath A. Proc Natl Acad Sci U S A 108 2717-2722 (2011)
- Degradation of macrolide antibiotics by ozone: a mechanistic case study with clarithromycin. Lange F, Cornelissen S, Kubac D, Sein MM, von Sonntag J, Hannich CB, Golloch A, Heipieper HJ, Möder M, von Sonntag C. Chemosphere 65 17-23 (2006)
- Effects of nucleotide substitution and modification on the stability and structure of helix 69 from 28S rRNA. Sumita M, Desaulniers JP, Chang YC, Chui HM, Clos L, Chow CS. RNA 11 1420-1429 (2005)
- In vitro reconstitution of EryCIII activity for the preparation of unnatural macrolides. Yuan Y, Chung HS, Leimkuhler C, Walsh CT, Kahne D, Walker S. J Am Chem Soc 127 14128-14129 (2005)
- Mutational analysis of 16S and 23S rRNA genes of Thermus thermophilus. Gregory ST, Carr JF, Rodriguez-Correa D, Dahlberg AE. J Bacteriol 187 4804-4812 (2005)
- Precursor directed biosynthesis of an orthogonally functional erythromycin analogue: selectivity in the ribosome macrolide binding pocket. Harvey CJ, Puglisi JD, Pande VS, Cane DE, Khosla C. J Am Chem Soc 134 12259-12265 (2012)
- Substrate specificity of the macrolide-glycosylating enzyme pair DesVII/DesVIII: opportunities, limitations, and mechanistic hypotheses. Borisova SA, Zhang C, Takahashi H, Zhang H, Wong AW, Thorson JS, Liu HW. Angew Chem Int Ed Engl 45 2748-2753 (2006)
- Kinetics of drug-ribosome interactions defines the cidality of macrolide antibiotics. Svetlov MS, Vázquez-Laslop N, Mankin AS. Proc Natl Acad Sci U S A 114 13673-13678 (2017)
- Pharmacokinetics of tildipirosin in bovine plasma, lung tissue, and bronchial fluid (from live, nonanesthetized cattle). Menge M, Rose M, Bohland C, Zschiesche E, Kilp S, Metz W, Allan M, Röpke R, Nürnberger M. J Vet Pharmacol Ther 35 550-559 (2012)
- An indigenous posttranscriptional modification in the ribosomal peptidyl transferase center confers resistance to an array of protein synthesis inhibitors. Toh SM, Mankin AS. J Mol Biol 380 593-597 (2008)
- Effect of codon adaptation on codon-level and gene-level translation efficiency in vivo. Nakahigashi K, Takai Y, Shiwa Y, Wada M, Honma M, Yoshikawa H, Tomita M, Kanai A, Mori H. BMC Genomics 15 1115 (2014)
- Effects on translation pausing of alterations in protein and RNA components of the ribosome exit tunnel. Lawrence MG, Lindahl L, Zengel JM. J Bacteriol 190 5862-5869 (2008)
- Structural basis for cross-resistance to ribosomal PTC antibiotics. Davidovich C, Bashan A, Yonath A. Proc Natl Acad Sci U S A 105 20665-20670 (2008)
- Structures of triacetyloleandomycin and mycalamide A bind to the large ribosomal subunit of Haloarcula marismortui. Gürel G, Blaha G, Steitz TA, Moore PB. Antimicrob Agents Chemother 53 5010-5014 (2009)
- The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics. Auerbach T, Mermershtain I, Davidovich C, Bashan A, Belousoff M, Wekselman I, Zimmerman E, Xiong L, Klepacki D, Arakawa K, Kinashi H, Mankin AS, Yonath A. Proc Natl Acad Sci U S A 107 1983-1988 (2010)
- L22 ribosomal protein and effect of its mutation on ribosome resistance to erythromycin. Davydova N, Streltsov V, Wilce M, Liljas A, Garber M. J Mol Biol 322 635-644 (2002)
- Letter Novel mutation in 23S rRNA that confers low-level resistance to clarithromycin in Helicobacter pylori. Rimbara E, Noguchi N, Kawai T, Sasatsu M. Antimicrob Agents Chemother 52 3465-3466 (2008)
- A genome-wide screen in Saccharomyces cerevisiae reveals a critical role for the mitochondria in the toxicity of a trichothecene mycotoxin. McLaughlin JE, Bin-Umer MA, Tortora A, Mendez N, McCormick S, Tumer NE. Proc Natl Acad Sci U S A 106 21883-21888 (2009)
- Antibiotic-specific differences in the response of Staphylococcus aureus to treatment with antimicrobials combined with manuka honey. Liu M, Lu J, Müller P, Turnbull L, Burke CM, Schlothauer RC, Carter DA, Whitchurch CB, Harry EJ. Front Microbiol 5 779 (2014)
- Identification of novel macrolides with antibacterial, anti-inflammatory and type I and III IFN-augmenting activity in airway epithelium. Porter JD, Watson J, Roberts LR, Gill SK, Groves H, Dhariwal J, Almond MH, Wong E, Walton RP, Jones LH, Tregoning J, Kilty I, Johnston SL, Edwards MR. J Antimicrob Chemother 71 2767-2781 (2016)
- In vitro ribosome synthesis and evolution through ribosome display. Hammerling MJ, Fritz BR, Yoesep DJ, Kim DS, Carlson ED, Jewett MC. Nat Commun 11 1108 (2020)
- Revisiting the mechanism of macrolide-antibiotic resistance mediated by ribosomal protein L22. Moore SD, Sauer RT. Proc Natl Acad Sci U S A 105 18261-18266 (2008)
- Macrolide-lincosamide-resistant phenotypes and genotypes of Staphylococcus aureus isolated from bovine clinical mastitis. Wang Y, Wu CM, Lu LM, Ren GW, Cao XY, Shen JZ. Vet Microbiol 130 118-125 (2008)
- Nascent peptide assists the ribosome in recognizing chemically distinct small molecules. Gupta P, Liu B, Klepacki D, Gupta V, Schulten K, Mankin AS, Vázquez-Laslop N. Nat Chem Biol 12 153-158 (2016)
- The structures of antibiotics bound to the E site region of the 50 S ribosomal subunit of Haloarcula marismortui: 13-deoxytedanolide and girodazole. Schroeder SJ, Blaha G, Tirado-Rives J, Steitz TA, Moore PB. J Mol Biol 367 1471-1479 (2007)
- Glycosylation steps during spiramycin biosynthesis in Streptomyces ambofaciens: involvement of three glycosyltransferases and their interplay with two auxiliary proteins. Nguyen HC, Karray F, Lautru S, Gagnat J, Lebrihi A, Huynh TD, Pernodet JL. Antimicrob Agents Chemother 54 2830-2839 (2010)
- Isolation of antibiotic resistance mutations in the rRNA by using an in vitro selection system. Cochella L, Green R. Proc Natl Acad Sci U S A 101 3786-3791 (2004)
- Ketolide resistance in Streptococcus pyogenes correlates with the degree of rRNA dimethylation by Erm. Douthwaite S, Jalava J, Jakobsen L. Mol Microbiol 58 613-622 (2005)
- Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. Long KS, Munck C, Andersen TM, Schaub MA, Hobbie SN, Böttger EC, Vester B. Antimicrob Agents Chemother 54 4705-4713 (2010)
- Bactobolin resistance is conferred by mutations in the L2 ribosomal protein. Chandler JR, Truong TT, Silva PM, Seyedsayamdost MR, Carr G, Radey M, Jacobs MA, Sims EH, Clardy J, Greenberg EP. mBio 3 e00499-12 (2012)
- In vitro activities of ABT-773 and other antimicrobials against human mycoplasmas. Waites KB, Crabb DM, Duffy LB. Antimicrob Agents Chemother 47 39-42 (2003)
- Molecular architecture of DesI: a key enzyme in the biosynthesis of desosamine. Burgie ES, Holden HM. Biochemistry 46 8999-9006 (2007)
- A Massively Parallel Selection of Small Molecule-RNA Motif Binding Partners Informs Design of an Antiviral from Sequence. Childs-Disney JL, Tran T, Vummidi BR, Velagapudi SP, Haniff HS, Matsumoto Y, Crynen G, Southern MR, Biswas A, Wang ZF, Tellinghuisen TL, Disney MD. Chem 4 2384-2404 (2018)
- A structure-based strategy to identify new molecular scaffolds targeting the bacterial ribosomal A-site. Foloppe N, Chen IJ, Davis B, Hold A, Morley D, Howes R. Bioorg Med Chem 12 935-947 (2004)
- Diversity of 23S rRNA genes within individual prokaryotic genomes. Pei A, Nossa CW, Chokshi P, Blaser MJ, Yang L, Rosmarin DM, Pei Z. PLoS One 4 e5437 (2009)
- Historical Article From the structure and function of the ribosome to new antibiotics (Nobel Lecture). Steitz TA. Angew Chem Int Ed Engl 49 4381-4398 (2010)
- Production of hybrid 16-membered macrolides by expressing combinations of polyketide synthase genes in engineered Streptomyces fradiae hosts. Reeves CD, Ward SL, Revill WP, Suzuki H, Marcus M, Petrakovsky OV, Marquez S, Fu H, Dong SD, Katz L. Chem Biol 11 1465-1472 (2004)
- SEARCHGTr: a program for analysis of glycosyltransferases involved in glycosylation of secondary metabolites. Kamra P, Gokhale RS, Mohanty D. Nucleic Acids Res 33 W220-5 (2005)
- Binding of Macrolide Antibiotics Leads to Ribosomal Selection against Specific Substrates Based on Their Charge and Size. Sothiselvam S, Neuner S, Rigger L, Klepacki D, Micura R, Vázquez-Laslop N, Mankin AS. Cell Rep 16 1789-1799 (2016)
- Conjugation with polyamines enhances the antibacterial and anticancer activity of chloramphenicol. Kostopoulou ON, Kouvela EC, Magoulas GE, Garnelis T, Panagoulias I, Rodi M, Papadopoulos G, Mouzaki A, Dinos GP, Papaioannou D, Kalpaxis DL. Nucleic Acids Res 42 8621-8634 (2014)
- Inhibition of human peptide deformylase disrupts mitochondrial function. Escobar-Alvarez S, Gardner J, Sheth A, Manfredi G, Yang G, Ouerfelli O, Heaney ML, Scheinberg DA. Mol Cell Biol 30 5099-5109 (2010)
- Methylation at nucleotide G745 or G748 in 23S rRNA distinguishes Gram-negative from Gram-positive bacteria. Liu M, Douthwaite S. Mol Microbiol 44 195-204 (2002)
- Mutagenesis of the modified bases, m(5)U1939 and psi2504, in Escherichia coli 23S rRNA. Persaud C, Lu Y, Vila-Sanjurjo A, Campbell JL, Finley J, O'Connor M. Biochem Biophys Res Commun 392 223-227 (2010)
- Mycobacterial HflX is a ribosome splitting factor that mediates antibiotic resistance. Rudra P, Hurst-Hess KR, Cotten KL, Partida-Miranda A, Ghosh P. Proc Natl Acad Sci U S A 117 629-634 (2020)
- Pharmacokinetics of tildipirosin in porcine plasma, lung tissue, and bronchial fluid and effects of test conditions on in vitro activity against reference strains and field isolates of Actinobacillus pleuropneumoniae. Rose M, Menge M, Bohland C, Zschiesche E, Wilhelm C, Kilp S, Metz W, Allan M, Röpke R, Nürnberger M. J Vet Pharmacol Ther 36 140-153 (2013)
- Role of 16S rRNA Helix 44 in Ribosomal Resistance to Hygromycin B. Pfister P, Risch M, Brodersen DE, Böttger EC. Antimicrob Agents Chemother 47 1496-1502 (2003)
- Sequence-dependent elongation dynamics on macrolide-bound ribosomes. Johansson M, Chen J, Tsai A, Kornberg G, Puglisi JD. Cell Rep 7 1534-1546 (2014)
- Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus. Matzov D, Eyal Z, Benhamou RI, Shalev-Benami M, Halfon Y, Krupkin M, Zimmerman E, Rozenberg H, Bashan A, Fridman M, Yonath A. Nucleic Acids Res 45 10284-10292 (2017)
- Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. Berkov-Zrihen Y, Green KD, Labby KJ, Feldman M, Garneau-Tsodikova S, Fridman M. J Med Chem 56 5613-5625 (2013)
- Crystal structure of RlmAI: implications for understanding the 23S rRNA G745/G748-methylation at the macrolide antibiotic-binding site. Das K, Acton T, Chiang Y, Shih L, Arnold E, Montelione GT. Proc Natl Acad Sci U S A 101 4041-4046 (2004)
- Erythromycin resistance by L4/L22 mutations and resistance masking by drug efflux pump deficiency. Lovmar M, Nilsson K, Lukk E, Vimberg V, Tenson T, Ehrenberg M. EMBO J 28 736-744 (2009)
- A flexible loop in yeast ribosomal protein L11 coordinates P-site tRNA binding. Rhodin MH, Dinman JD. Nucleic Acids Res 38 8377-8389 (2010)
- Antibiotic-induced ribosomal assembly defects result from changes in the synthesis of ribosomal proteins. Siibak T, Peil L, Dönhöfer A, Tats A, Remm M, Wilson DN, Tenson T, Remme J. Mol Microbiol 80 54-67 (2011)
- Construction of the octose 8-phosphate intermediate in lincomycin A biosynthesis: characterization of the reactions catalyzed by LmbR and LmbN. Sasaki E, Lin CI, Lin KY, Liu HW. J Am Chem Soc 134 17432-17435 (2012)
- Evaluating Ketoreductase Exchanges as a Means of Rationally Altering Polyketide Stereochemistry. Annaval T, Paris C, Leadlay PF, Jacob C, Weissman KJ. Chembiochem 16 1357-1364 (2015)
- Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant. Halfon Y, Matzov D, Eyal Z, Bashan A, Zimmerman E, Kjeldgaard J, Ingmer H, Yonath A. Sci Rep 9 11460 (2019)
- Expanding the Scope of Protein Synthesis Using Modified Ribosomes. Dedkova LM, Hecht SM. J Am Chem Soc 141 6430-6447 (2019)
- Regulation of a Bacteroides operon that controls excision and transfer of the conjugative transposon CTnDOT. Wang Y, Shoemaker NB, Salyers AA. J Bacteriol 186 2548-2557 (2004)
- Scaffold hopping by "fuzzy" pharmacophores and its application to RNA targets. Tanrikulu Y, Nietert M, Scheffer U, Proschak E, Grabowski K, Schneider P, Weidlich M, Karas M, Göbel M, Schneider G. Chembiochem 8 1932-1936 (2007)
- Structure of 23S rRNA hairpin 35 and its interaction with the tylosin-resistance methyltransferase RlmAII. Lebars I, Yoshizawa S, Stenholm AR, Guittet E, Douthwaite S, Fourmy D. EMBO J 22 183-192 (2003)
- A crevice adjoining the ribosome tunnel: hints for cotranslational folding. Amit M, Berisio R, Baram D, Harms J, Bashan A, Yonath A. FEBS Lett 579 3207-3213 (2005)
- An extensive network of information flow through the B1b/c intersubunit bridge of the yeast ribosome. Rhodin MH, Dinman JD. PLoS One 6 e20048 (2011)
- Covalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis. McCusker KP, Medzihradszky KF, Shiver AL, Nichols RJ, Yan F, Maltby DA, Gross CA, Fujimori DG. J Am Chem Soc 134 18074-18081 (2012)
- Dynamics of the context-specific translation arrest by chloramphenicol and linezolid. Choi J, Marks J, Zhang J, Chen DH, Wang J, Vázquez-Laslop N, Mankin AS, Puglisi JD. Nat Chem Biol 16 310-317 (2020)
- Effect of polyamines on the inhibition of peptidyltransferase by antibiotics: revisiting the mechanism of chloramphenicol action. Xaplanteri MA, Andreou A, Dinos GP, Kalpaxis DL. Nucleic Acids Res 31 5074-5083 (2003)
- Engineered biosynthesis of hybrid macrolide polyketides containing D-angolosamine and D-mycaminose moieties. Schell U, Haydock SF, Kaja AL, Carletti I, Lill RE, Read E, Sheehan LS, Low L, Fernandez MJ, Grolle F, McArthur HA, Sheridan RM, Leadlay PF, Wilkinson B, Gaisser S. Org Biomol Chem 6 3315-3327 (2008)
- Fluorescence polarization method to characterize macrolide-ribosome interactions. Yan K, Hunt E, Berge J, May E, Copeland RA, Gontarek RR. Antimicrob Agents Chemother 49 3367-3372 (2005)
- Non-bulk-like solvent behavior in the ribosome exit tunnel. Lucent D, Snow CD, Aitken CE, Pande VS. PLoS Comput Biol 6 e1000963 (2010)
- Prognosis and treatment of desquamative inflammatory vaginitis. Sobel JD, Reichman O, Misra D, Yoo W. Obstet Gynecol 117 850-855 (2011)
- Small protein B interacts with the large and the small subunits of a stalled ribosome during trans-translation. Hallier M, Desreac J, Felden B. Nucleic Acids Res 34 1935-1943 (2006)
- Toward ribosomal RNA catalytic activity in the absence of protein. Anderson RM, Kwon M, Strobel SA. J Mol Evol 64 472-483 (2007)
- Transcription factor CecR (YbiH) regulates a set of genes affecting the sensitivity of Escherichia coli against cefoperazone and chloramphenicol. Yamanaka Y, Shimada T, Yamamoto K, Ishihama A. Microbiology (Reading) 162 1253-1264 (2016)
- Characterization of a 30S ribosomal subunit assembly intermediate found in Escherichia coli cells growing with neomycin or paromomycin. Foster C, Champney WS. Arch Microbiol 189 441-449 (2008)
- Path of nascent polypeptide in exit tunnel revealed by molecular dynamics simulation of ribosome. Ishida H, Hayward S. Biophys J 95 5962-5973 (2008)
- Peptide-mediated macrolide resistance reveals possible specific interactions in the nascent peptide exit tunnel. Vimberg V, Xiong L, Bailey M, Tenson T, Mankin A. Mol Microbiol 54 376-385 (2004)
- Proliferation of antibiotic resistance genes in microbial consortia of sequencing batch reactors (SBRs) upon exposure to trace erythromycin or erythromycin-H2O. Fan C, He J. Water Res 45 3098-3106 (2011)
- Properties and identification of antibiotic drug targets. Bakheet TM, Doig AJ. BMC Bioinformatics 11 195 (2010)
- Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides. Almutairi MM, Park SR, Rose S, Hansen DA, Vázquez-Laslop N, Douthwaite S, Sherman DH, Mankin AS. Proc Natl Acad Sci U S A 112 12956-12961 (2015)
- Ribosomal Mutations Conferring Macrolide Resistance in Legionella pneumophila. Descours G, Ginevra C, Jacotin N, Forey F, Chastang J, Kay E, Etienne J, Lina G, Doublet P, Jarraud S. Antimicrob Agents Chemother 61 e02188-16 (2017)
- The methymycin/pikromycin pathway: a model for metabolic diversity in natural product biosynthesis. Kittendorf JD, Sherman DH. Bioorg Med Chem 17 2137-2146 (2009)
- In Vitro Isolation and Characterization of Oxazolidinone-Resistant Mycobacterium tuberculosis. McNeil MB, Dennison DD, Shelton CD, Parish T. Antimicrob Agents Chemother 61 e01296-17 (2017)
- A conserved chloramphenicol binding site at the entrance to the ribosomal peptide exit tunnel. Long KS, Porse BT. Nucleic Acids Res 31 7208-7215 (2003)
- Comparison of the sensitivities of WaterLOGSY and saturation transfer difference NMR experiments. Antanasijevic A, Ramirez B, Caffrey M. J Biomol NMR 60 37-44 (2014)
- Effects of a number of classes of 50S inhibitors on stop codon readthrough during protein synthesis. Thompson J, Pratt CA, Dahlberg AE. Antimicrob Agents Chemother 48 4889-4891 (2004)
- Epidemiology of macrolide and/or lincosamide resistant Streptococcus pneumoniae clinical isolates with ribosomal mutations. Doktor SZ, Shortridge VD, Beyer JM, Flamm RK. Diagn Microbiol Infect Dis 49 47-52 (2004)
- Erythromycin, roxithromycin, and clarithromycin: use of slow-binding kinetics to compare their in vitro interaction with a bacterial ribosomal complex active in peptide bond formation. Dinos GP, Connell SR, Nierhaus KH, Kalpaxis DL. Mol Pharmacol 63 617-623 (2003)
- Genetic evidence for a regulatory pathway controlling alternative oxidase production in Neurospora crassa. Descheneau AT, Cleary IA, Nargang FE. Genetics 169 123-135 (2005)
- Tailoring pathway modularity in the biosynthesis of erythromycin analogs heterologously engineered in E. coli. Zhang G, Li Y, Fang L, Pfeifer BA. Sci Adv 1 e1500077 (2015)
- Antibiotics that bind to the A site of the large ribosomal subunit can induce mRNA translocation. Ermolenko DN, Cornish PV, Ha T, Noller HF. RNA 19 158-166 (2013)
- Ketolide antimicrobial activity persists after disruption of interactions with domain II of 23S rRNA. Novotny GW, Jakobsen L, Andersen NM, Poehlsgaard J, Douthwaite S. Antimicrob Agents Chemother 48 3677-3683 (2004)
- Mercury methylation and the microbial consortium in periphyton of tropical macrophytes: effect of different inhibitors. Correia RR, Miranda MR, Guimarães JR. Environ Res 112 86-91 (2012)
- Structural analysis of QdtB, an aminotransferase required for the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose. Thoden JB, Schäffer C, Messner P, Holden HM. Biochemistry 48 1553-1561 (2009)
- The tylosin-resistance methyltransferase RlmA(II) (TlrB) modifies the N-1 position of 23S rRNA nucleotide G748. Douthwaite S, Crain PF, Liu M, Poehlsgaard J. J Mol Biol 337 1073-1077 (2004)
- Vancomycin analogues containing monosaccharides exhibit improved antibiotic activity: a combined one-pot enzymatic glycosylation and chemical diversification strategy. Thayer DA, Wong CH. Chem Asian J 1 445-452 (2006)
- 23S rRNA 2058A-->G alteration mediates ketolide resistance in combination with deletion in L22. Berisio R, Corti N, Pfister P, Yonath A, Böttger EC. Antimicrob Agents Chemother 50 3816-3823 (2006)
- Aminoglycosides and other factors promoting stop codon readthrough in human cells. Diop D, Chauvin C, Jean-Jean O. C R Biol 330 71-79 (2007)
- Biolog Phenotype Microarray Is a Tool for the Identification of Multidrug Resistance Efflux Pump Inducers. Blanco P, Corona F, Martínez JL. Antimicrob Agents Chemother 62 e01263-18 (2018)
- Chemistry and biology of macrolide antiparasitic agents. Lee Y, Choi JY, Fu H, Harvey C, Ravindran S, Roush WR, Boothroyd JC, Khosla C. J Med Chem 54 2792-2804 (2011)
- Induction of efflux-mediated macrolide resistance in Streptococcus pneumoniae. Chancey ST, Zhou X, Zähner D, Stephens DS. Antimicrob Agents Chemother 55 3413-3422 (2011)
- Monitoring the Decrease in Susceptibility to Ribosomal RNAs Targeting Antimicrobials and Its Molecular Basis in Clinical Mycoplasma bovis Isolates over Time. Khalil D, Becker CAM, Tardy F. Microb Drug Resist 23 799-811 (2017)
- Mutation from guanine to adenine in 25S rRNA at the position equivalent to E. coli A2058 does not confer erythromycin sensitivity in Sacchromyces cerevisae. Bommakanti AS, Lindahl L, Zengel JM. RNA 14 460-464 (2008)
- Resistance-nodulation-division efflux pump acrAB is modulated by florfenicol and contributes to drug resistance in the fish pathogen Piscirickettsia salmonis. Sandoval R, Oliver C, Valdivia S, Valenzuela K, Haro RE, Sánchez P, Olavarría VH, Valenzuela P, Avendaño-Herrera R, Romero A, Cárcamo JG, Figueroa JE, Yáñez AJ. FEMS Microbiol Lett 363 fnw102 (2016)
- Time-resolved binding of azithromycin to Escherichia coli ribosomes. Petropoulos AD, Kouvela EC, Starosta AL, Wilson DN, Dinos GP, Kalpaxis DL. J Mol Biol 385 1179-1192 (2009)
- Biosynthetic pathway toward carbohydrate-like moieties of alnumycins contains unusual steps for C-C bond formation and cleavage. Oja T, Klika KD, Appassamy L, Sinkkonen J, Mäntsälä P, Niemi J, Metsä-Ketelä M. Proc Natl Acad Sci U S A 109 6024-6029 (2012)
- Characterization and engineering of the biosynthesis gene cluster for antitumor macrolides PM100117 and PM100118 from a marine actinobacteria: generation of a novel improved derivative. Salcedo RG, Olano C, Gómez C, Fernández R, Braña AF, Méndez C, de la Calle F, Salas JA. Microb Cell Fact 15 44 (2016)
- Characterization of a novel antibacterial agent that inhibits bacterial translation. Böddeker N, Bahador G, Gibbs C, Mabery E, Wolf J, Xu L, Watson J. RNA 8 1120-1128 (2002)
- Cosegregation of novel mitochondrial 16S rRNA gene mutations with the age-associated T414G variant in human cybrids. Seibel P, Di Nunno C, Kukat C, Schäfer I, Del Bo R, Bordoni A, Comi GP, Schön A, Capuano F, Latorre D, Villani G. Nucleic Acids Res 36 5872-5881 (2008)
- Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii. Li Z, Guo Q, Zheng L, Ji Y, Xie YT, Lai DH, Lun ZR, Suo X, Gao N. Cell Res 27 1275-1288 (2017)
- Free and bound state structures of 6-O-methyl homoerythromycins and epitope mapping of their interactions with ribosomes. Novak P, Barber J, Cikos A, Arsic B, Plavec J, Lazarevski G, Tepes P, Kosutić-Hulita N. Bioorg Med Chem 17 5857-5867 (2009)
- Polyamines affect diversely the antibiotic potency: insight gained from kinetic studies of the blasticidin S AND spiramycin interactions with functional ribosomes. Petropoulos AD, Xaplanteri MA, Dinos GP, Wilson DN, Kalpaxis DL. J Biol Chem 279 26518-26525 (2004)
- Revealing unique properties of the ribosome using a network based analysis. David-Eden H, Mandel-Gutfreund Y. Nucleic Acids Res 36 4641-4652 (2008)
- Structural basis for C-ribosylation in the alnumycin A biosynthetic pathway. Oja T, Niiranen L, Sandalova T, Klika KD, Niemi J, Mäntsälä P, Schneider G, Metsä-Ketelä M. Proc Natl Acad Sci U S A 110 1291-1296 (2013)
- Accumulation and turnover of 23S ribosomal RNA in azithromycin-inhibited ribonuclease mutant strains of Escherichia coli. Silvers JA, Champney WS. Arch Microbiol 184 66-77 (2005)
- Antibiotic selectivity for prokaryotic vs. eukaryotic decoding sites. Xie Y, Dix AV, Tor Y. Chem Commun (Camb) 46 5542-5544 (2010)
- On the mechanism of action of 9-O-arylalkyloxime derivatives of 6-O-mycaminosyltylonolide, a new class of 16-membered macrolide antibiotics. Karahalios P, Kalpaxis DL, Fu H, Katz L, Wilson DN, Dinos GP. Mol Pharmacol 70 1271-1280 (2006)
- Ribosomal crystallography: from poorly diffracting microcrystals to high-resolution structures. Gluehmann M, Zarivach R, Bashan A, Harms J, Schluenzen F, Bartels H, Agmon I, Rosenblum G, Pioletti M, Auerbach T, Avila H, Hansen HA, Franceschi F, Yonath A. Methods 25 292-302 (2001)
- The ribosome as a drug target. Böttger EC. Trends Biotechnol 24 145-147 (2006)
- Distinct mode of interaction of a novel ketolide antibiotic that displays enhanced antimicrobial activity. Kouvela EC, Kalpaxis DL, Wilson DN, Dinos GP. Antimicrob Agents Chemother 53 1411-1419 (2009)
- ErmK leader peptide : amino acid sequence critical for induction by erythromycin. Kwon AR, Min YH, Yoon EJ, Kim JA, Shim MJ, Choi EC. Arch Pharm Res 29 1154-1157 (2006)
- High prevalence and molecular analysis of macrolide-nonsusceptible Moraxella catarrhalis isolated from nasopharynx of healthy children in China. Liu Y, Zhao C, Zhang F, Chen H, Chen M, Wang H. Microb Drug Resist 18 417-426 (2012)
- Induction of macrolide resistance in Mycoplasma gallisepticum in vitro and its resistance-related mutations within domain V of 23S rRNA. Wu CM, Wu H, Ning Y, Wang J, Du X, Shen J. FEMS Microbiol Lett 247 199-205 (2005)
- Inhibition of protein synthesis on the ribosome by tildipirosin compared with other veterinary macrolides. Andersen NM, Poehlsgaard J, Warrass R, Douthwaite S. Antimicrob Agents Chemother 56 6033-6036 (2012)
- NusG-Dependent RNA Polymerase Pausing and Tylosin-Dependent Ribosome Stalling Are Required for Tylosin Resistance by Inducing 23S rRNA Methylation in Bacillus subtilis. Yakhnin H, Yakhnin AV, Mouery BL, Mandell ZF, Karbasiafshar C, Kashlev M, Babitzke P. mBio 10 e02665-19 (2019)
- The Response of Enterococcus faecalis V583 to Chloramphenicol Treatment. Aakra A, Vebø H, Indahl U, Snipen L, Gjerstad O, Lunde M, Nes IF. Int J Microbiol 2010 483048 (2010)
- Assessment of Draxxin® (tulathromycin) as an inhibitor of in vitro growth of Babesia bovis, Babesia bigemina and Theileria equi. Silva MG, Villarino NF, Knowles DP, Suarez CE. Int J Parasitol Drugs Drug Resist 8 265-270 (2018)
- Base pairs and pseudo pairs observed in RNA-ligand complexes. Kondo J, Westhof E. J Mol Recognit 23 241-252 (2010)
- Building of neomycin-nucleobase-amino acid conjugates for the inhibition of oncogenic miRNAs biogenesis. Vo DD, Becquart C, Tran TPA, Di Giorgio A, Darfeuille F, Staedel C, Duca M. Org Biomol Chem 16 6262-6274 (2018)
- Characterization of the interactions between tetracycline antibiotics and microbial extracellular polymeric substances with spectroscopic approaches. Song C, Sun XF, Xing SF, Xia PF, Shi YJ, Wang SG. Environ Sci Pollut Res Int 21 1786-1795 (2014)
- Identification of an alternative oxidase induction motif in the promoter region of the aod-1 gene in Neurospora crassa. Chae MS, Lin CC, Kessler KE, Nargang CE, Tanton LL, Hahn LB, Nargang FE. Genetics 175 1597-1606 (2007)
- Impact of ribosomal modification on the binding of the antibiotic telithromycin using a combined grand canonical monte carlo/molecular dynamics simulation approach. Small MC, Lopes P, Andrade RB, Mackerell AD. PLoS Comput Biol 9 e1003113 (2013)
- Microarray expression profiling of Yersinia pestis in response to chloramphenicol. Qiu J, Zhou D, Qin L, Han Y, Wang X, DU Z, Song Y, Yang R. FEMS Microbiol Lett 263 26-31 (2006)
- Molecular mechanisms by which rRNA mutations confer resistance to clindamycin. Poehlsgaard J, Pfister P, Böttger EC, Douthwaite S. Antimicrob Agents Chemother 49 1553-1555 (2005)
- Synthesis of novel lincomycin derivatives and their in vitro antibacterial activities. Umemura E, Wakiyama Y, Kumura K, Ueda K, Masaki S, Watanabe T, Yamamoto M, Hirai Y, Fushimi H, Yoshida T, Ajito K. J Antibiot (Tokyo) 66 195-198 (2013)
- The contribution of common rpsL mutations in Escherichia coli to sensitivity to ribosome targeting antibiotics. Pelchovich G, Schreiber R, Zhuravlev A, Gophna U. Int J Med Microbiol 303 558-562 (2013)
- Anti-Salmonella Activity of Volatile Compounds of Vietnam Coriander. Fujita K, Chavasiri W, Kubo I. Phytother Res 29 1081-1087 (2015)
- Context-specific action of macrolide antibiotics on the eukaryotic ribosome. Svetlov MS, Koller TO, Meydan S, Shankar V, Klepacki D, Polacek N, Guydosh NR, Vázquez-Laslop N, Wilson DN, Mankin AS. Nat Commun 12 2803 (2021)
- Inhibition of protein synthesis by aminoglycoside-arginine conjugates. Carriere M, Vijayabaskar V, Applefield D, Harvey I, Garneau P, Lorsch J, Lapidot A, Pelletier J. RNA 8 1267-1279 (2002)
- Insights into the mode of action of novel fluoroketolides, potent inhibitors of bacterial protein synthesis. Krokidis MG, Márquez V, Wilson DN, Kalpaxis DL, Dinos GP. Antimicrob Agents Chemother 58 472-480 (2014)
- On the use of the antibiotic chloramphenicol to target polypeptide chain mimics to the ribosomal exit tunnel. Mamos P, Krokidis MG, Papadas A, Karahalios P, Starosta AL, Wilson DN, Kalpaxis DL, Dinos GP. Biochimie 95 1765-1772 (2013)
- Searching for a wrench to throw into the splicing machine. Jurica MS. Nat Chem Biol 4 3-6 (2008)
- Sequence context dependence of tandem guanine:adenine mismatch conformations in RNA: a continuum solvent analysis. Villescas-Diaz G, Zacharias M. Biophys J 85 416-425 (2003)
- Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics. Nicholson D, Edwards TA, O'Neill AJ, Ranson NA. Structure 28 1087-1100.e3 (2020)
- Targeting RNAs with tobramycin analogues. Liang FS, Wang SK, Nakatani T, Wong CH. Angew Chem Int Ed Engl 43 6496-6500 (2004)
- Adsorption and transformation of selected human-used macrolide antibacterial agents with iron(III) and manganese(IV) oxides. Feitosa-Felizzola J, Hanna K, Chiron S. Environ Pollut 157 1317-1322 (2009)
- Comparative proteomic analysis reveals drug resistance of Staphylococcus xylosus ATCC700404 under tylosin stress. Liu X, Wang J, Chen M, Che R, Ding W, Yu F, Zhou Y, Cui W, Xiaoxu X, God'spower BO, Li Y. BMC Vet Res 15 224 (2019)
- Design, synthesis, and biological evaluation of BODIPY-erythromycin probes for bacterial ribosomes. Li J, Kim IH, Roche ED, Beeman D, Lynch AS, Ding CZ, Ma Z. Bioorg Med Chem Lett 16 794-797 (2006)
- Discovery and analysis of 4H-pyridopyrimidines, a class of selective bacterial protein synthesis inhibitors. Ribble W, Hill WE, Ochsner UA, Jarvis TC, Guiles JW, Janjic N, Bullard JM. Antimicrob Agents Chemother 54 4648-4657 (2010)
- Macrolides for KCNJ5-mutated aldosterone-producing adenoma (MAPA): design of a study for personalized diagnosis of primary aldosteronism. Maiolino G, Ceolotto G, Battistel M, Barbiero G, Cesari M, Amar L, Caroccia B, Padrini R, Azizi M, Rossi GP. Blood Press 27 200-205 (2018)
- Recognition elements in rRNA for the tylosin resistance methyltransferase RlmA(II). Lebars I, Husson C, Yoshizawa S, Douthwaite S, Fourmy D. J Mol Biol 372 525-534 (2007)
- SorF: a glycosyltransferase with promiscuous donor substrate specificity in vitro. Kopp M, Rupprath C, Irschik H, Bechthold A, Elling L, Müller R. Chembiochem 8 813-819 (2007)
- Structural and functional insights into esterase-mediated macrolide resistance. Zieliński M, Park J, Sleno B, Berghuis AM. Nat Commun 12 1732 (2021)
- Synthesis and antimicrobial activity of chloramphenicol-polyamine conjugates. Magoulas GE, Kostopoulou ON, Garnelis T, Athanassopoulos CM, Kournoutou GG, Leotsinidis M, Dinos GP, Papaioannou D, Kalpaxis DL. Bioorg Med Chem 23 3163-3174 (2015)
- The Antibacterial Potential of Honeydew Honey Produced by Stingless Bee (Heterotrigona itama) against Antibiotic Resistant Bacteria. Ng WJ, Sit NW, Ooi PA, Ee KY, Lim TM. Antibiotics (Basel) 9 E871 (2020)
- The Peptidyl Transferase Center: a Window to the Past. Tirumalai MR, Rivas M, Tran Q, Fox GE. Microbiol Mol Biol Rev 85 e0010421 (2021)
- Two genes involved in clindamycin resistance of Bacillus licheniformis and Bacillus paralicheniformis identified by comparative genomic analysis. Jeong DW, Lee B, Heo S, Oh Y, Heo G, Lee JH. PLoS One 15 e0231274 (2020)
- Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A. Kaminishi T, Schedlbauer A, Fabbretti A, Brandi L, Ochoa-Lizarralde B, He CG, Milón P, Connell SR, Gualerzi CO, Fucini P. Nucleic Acids Res 43 10015-10025 (2015)
- Determination of In Vitro Activities of Solithromycin at Different pHs and Its Intracellular Activity against Clinical Isolates of Neisseria gonorrhoeae from a Laboratory Collection. Mallegol J, Fernandes P, Seah C, Guyard C, Melano RG. Antimicrob Agents Chemother 57 4322-4328 (2013)
- Intrinsic and selected resistance to antibiotics binding the ribosome: analyses of Brucella 23S rrn, L4, L22, EF-Tu1, EF-Tu2, efflux and phylogenetic implications. Halling SM, Jensen AE. BMC Microbiol 6 84 (2006)
- Methylation of 23S rRNA nucleotide G745 is a secondary function of the RlmAI methyltransferase. Liu M, Novotny GW, Douthwaite S. RNA 10 1713-1720 (2004)
- Phylogenetic analysis of antibiotic glycosyltransferases. Liang D, Qiao J. J Mol Evol 64 342-353 (2007)
- Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens. Kumar R, Rathy S, Hajare AK, Surase YB, Dullu J, Jadhav JS, Venkataramanan R, Chakrabarti A, Pandya M, Bhateja P, Ramkumar G, Das B. Bioorg Med Chem Lett 22 476-481 (2012)
- The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. Wekselman I, Zimmerman E, Davidovich C, Belousoff M, Matzov D, Krupkin M, Rozenberg H, Bashan A, Friedlander G, Kjeldgaard J, Ingmer H, Lindahl L, Zengel JM, Yonath A. Structure 25 1233-1241.e3 (2017)
- Antimicrobial Resistance Genes in Bacteria Isolated From Japanese Honey, and Their Potential for Conferring Macrolide and Lincosamide Resistance in the American Foulbrood Pathogen Paenibacillus larvae. Okamoto M, Kumagai M, Kanamori H, Takamatsu D. Front Microbiol 12 667096 (2021)
- Association of a novel preribosomal complex in Trypanosoma brucei determined by fluorescence resonance energy transfer. Wang L, Ciganda M, Williams N. Eukaryot Cell 12 322-329 (2013)
- Atypical Mutation in Neisseria gonorrhoeae 23S rRNA Associated with High-Level Azithromycin Resistance. Pham CD, Nash E, Liu H, Schmerer MW, Sharpe S, Woods G, Roland B, Schlanger K, St Cyr SB, Carlson J, Sellers K, Olsen A, Sanon R, Hardin H, Soge OO, Raphael BH, Kersh EN. Antimicrob Agents Chemother 65 e00885-20 (2021)
- Conformational analysis of oleandomycin and its 8-methylene-9-oxime derivative by NMR and molecular modelling. Novak P, Tomisić ZB, Tepes P, Lazarevski G, Plavec J, Turkalj G. Org Biomol Chem 3 39-47 (2005)
- Crystal structure of RlmM, the 2'O-ribose methyltransferase for C2498 of Escherichia coli 23S rRNA. Punekar AS, Shepherd TR, Liljeruhm J, Forster AC, Selmer M. Nucleic Acids Res 40 10507-10520 (2012)
- Desmethyl Macrolides: Synthesis and Evaluation of 4,8-Didesmethyl Telithromycin. Wagh B, Paul T, Glassford I, Debrosse C, Klepacki D, Small MC, Mackerell AD, Andrade RB. ACS Med Chem Lett 3 1013-1018 (2012)
- Direct entry to erythronolides via a cyclic bis[allene]. Liu K, Kim H, Ghosh P, Akhmedov NG, Williams LJ. J Am Chem Soc 133 14968-14971 (2011)
- Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance. Tsai K, Stojković V, Noda-Garcia L, Young ID, Myasnikov AG, Kleinman J, Palla A, Floor SN, Frost A, Fraser JS, Tawfik DS, Fujimori DG. Elife 11 e70017 (2022)
- Research Support, Non-U.S. Gov't Influence of mtDNA genetic variation on antibiotic therapy. Pacheu-Grau D, Gómez-Durán A, Montoya J, Ruiz-Pesini E. Pharmacogenomics 11 1185-1187 (2010)
- Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome. Pichkur EB, Paleskava A, Tereshchenkov AG, Kasatsky P, Komarova ES, Shiriaev DI, Bogdanov AA, Dontsova OA, Osterman IA, Sergiev PV, Polikanov YS, Myasnikov AG, Konevega AL. RNA 26 715-723 (2020)
- Lateral-flow immunoassay for detecting drug-induced inhibition of mitochondrial DNA replication and mtDNA-encoded protein synthesis. Nadanaciva S, Willis JH, Barker ML, Gharaibeh D, Capaldi RA, Marusich MF, Will Y. J Immunol Methods 343 1-12 (2009)
- Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates. Magee TV, Han S, McCurdy SP, Nguyen TT, Granskog K, Marr ES, Maguire BA, Huband MD, Chen JM, Subashi TA, Shanmugasundaram V. Bioorg Med Chem Lett 23 1727-1731 (2013)
- Parametrization of macrolide antibiotics using the force field toolkit. Pavlova A, Gumbart JC. J Comput Chem 36 2052-2063 (2015)
- Retargeting azithromycin analogues to have dual-modality antimalarial activity. Burns AL, Sleebs BE, Siddiqui G, De Paoli AE, Anderson D, Liffner B, Harvey R, Beeson JG, Creek DJ, Goodman CD, McFadden GI, Wilson DW. BMC Biol 18 133 (2020)
- Selection for high-level telithromycin resistance in Staphylococcus aureus yields mutants resulting from an rplB-to-rplV gene conversion-like event. Gentry DR, Holmes DJ. Antimicrob Agents Chemother 52 1156-1158 (2008)
- Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine. Syroegin EA, Aleksandrova EV, Polikanov YS. Nucleic Acids Res 50 7669-7679 (2022)
- Synthesis and antibacterial activity of 4''-O-heteroarylcarbamoyl derivatives of macrolide. Xu P, Liu L, Jin ZP, Wang GQ, Liu J, Li Y, Lei PS. Bioorg Med Chem Lett 18 5507-5511 (2008)
- Synthesis and antibacterial activity of a series of novel 9-O-acetyl- 4'-substituted 16-membered macrolides derived from josamycin. Zhao Z, Jin L, Xu Y, Zhu D, Liu Y, Liu C, Lei P. Bioorg Med Chem Lett 24 480-484 (2014)
- A high frequency of macrolide-lincosamide-streptogramin resistance determinants in Staphylococcus aureus isolated in South Korea. Kim HB, Lee B, Jang HC, Kim SH, Kang CI, Choi YJ, Park SW, Kim BS, Kim EC, Oh MD, Choe KW. Microb Drug Resist 10 248-254 (2004)
- Aptamer structures: a preview into regulatory pathways? Piganeau N, Schroeder R. Chem Biol 10 103-104 (2003)
- Derivatives of Ribosome-Inhibiting Antibiotic Chloramphenicol Inhibit the Biosynthesis of Bacterial Cell Wall. Louzoun Zada S, Green KD, Shrestha SK, Herzog IM, Garneau-Tsodikova S, Fridman M. ACS Infect Dis 4 1121-1129 (2018)
- Desmethyl Macrolides: Synthesis and Evaluation of 4,8,10-Tridesmethyl Cethromycin. Wagh B, Paul T, Debrosse C, Klepacki D, Small MC, Mackerell AD, Andrade RB. ACS Med Chem Lett 4 1114-1118 (2013)
- Identification of antibiotic clarithromycin binding peptide displayed by T7 phage particles. Morimura T, Noda N, Kato Y, Watanabe T, Saitoh T, Yamazaki T, Takada K, Aoki S, Ohta K, Ohshige M, Sakaguchi K, Sugawara F. J Antibiot (Tokyo) 59 625-632 (2006)
- Multiple enzymatic digestions and ion mobility separation improve quantification of bacterial ribosomal proteins by data independent acquisition liquid chromatography-mass spectrometry. Dator RP, Gaston KW, Limbach PA. Anal Chem 86 4264-4270 (2014)
- NMR and molecular modelling studies of the binding of amicetin antibiotic to conserved secondary structural motifs of 23S ribosomal RNAs. Donarski J, Shammas C, Banks R, Ramesh V. J Antibiot (Tokyo) 59 177-183 (2006)
- New Chloramphenicol Derivatives from the Viewpoint of Anticancer and Antimicrobial Activity. Giannopoulou PC, Missiri DA, Kournoutou GG, Sazakli E, Papadopoulos GE, Papaioannou D, Dinos GP, Athanassopoulos CM, Kalpaxis DL. Antibiotics (Basel) 8 E9 (2019)
- Potential key bases of ribosomal RNA to kingdom-specific spectra of antibiotic susceptibility and the possible archaeal origin of eukaryotes. Xie Q, Wang Y, Lin J, Qin Y, Wang Y, Bu W. PLoS One 7 e29468 (2012)
- Prediction of resistance to erythromycin in the genus Rickettsia by mutations in L22 ribosomal protein. Rolain JM, Raoult D. J Antimicrob Chemother 56 396-398 (2005)
- Repeated therapeutic dosing selects macrolide-resistant Campylobacter spp. in a turkey facility. Logue CM, Danzeisen GT, Sherwood JS, Thorsness JL, Mercier BM, Axtman JE. J Appl Microbiol 109 1379-1388 (2010)
- Synthesis and antibacterial activity of novel 11,12-cyclic carbonate azithromycin 4''-O-carbamate derivatives. Ma C, Liu Z, Song H, Jiang R, He F, Ma S. J Antibiot (Tokyo) 63 3-8 (2010)
- Synthesis and antibacterial activity of novel lincomycin derivatives. I. Enhancement of antibacterial activities by introduction of substituted azetidines. Kumura K, Wakiyama Y, Ueda K, Umemura E, Watanabe T, Shitara E, Fushimi H, Yoshida T, Ajito K. J Antibiot (Tokyo) 69 440-445 (2016)
- Targeting the A site RNA of the Escherichia coli ribosomal 30 S subunit by 2'-O-methyl oligoribonucleotides: a quantitative equilibrium dialysis binding assay and differential effects of aminoglycoside antibiotics. Abelian A, Walsh AP, Lentzen G, Aboul-Ela F, Gait MJ. Biochem J 383 201-208 (2004)
- Weapons in disguise--activating mechanisms and protecting group chemistry in nature. Kwan JC, Luesch H. Chemistry 16 13020-13029 (2010)
- A nascent proteome study combining click chemistry with 2DE. Osterman IA, Ustinov AV, Evdokimov DV, Korshun VA, Sergiev PV, Serebryakova MV, Demina IA, Galyamina MA, Govorun VM, Dontsova OA. Proteomics 13 17-21 (2013)
- Diglycine Enables Rapid Intrabacterial Hydrolysis for Activating Anbiotics against Gram-negative Bacteria. Wang J, Cooper DL, Zhan W, Wu D, He H, Sun S, Lovett ST, Xu B. Angew Chem Int Ed Engl 58 10631-10634 (2019)
- Glycosidase inhibition by macrolide antibiotics elucidated by STD-NMR spectroscopy. Sadeghi-Khomami A, Lumsden MD, Jakeman DL. Chem Biol 15 739-749 (2008)
- Identification of biotransformation products of macrolide and fluoroquinolone antimicrobials in membrane bioreactor treatment by ultrahigh-performance liquid chromatography/quadrupole time-of-flight mass spectrometry. Terzic S, Senta I, Matosic M, Ahel M. Anal Bioanal Chem 401 353-363 (2011)
- Novel antibacterial azetidine lincosamides. O'Dowd H, Lewis JG, Trias J, Asano R, Blais J, Lopez SL, Park CK, Wu C, Wang W, Gordeev MF. Bioorg Med Chem Lett 18 2645-2648 (2008)
- Phylogenetic sequence variations in bacterial rRNA affect species-specific susceptibility to drugs targeting protein synthesis. Akshay S, Bertea M, Hobbie SN, Oettinghaus B, Shcherbakov D, Böttger EC, Akbergenov R. Antimicrob Agents Chemother 55 4096-4102 (2011)
- Structure of Dirithromycin Bound to the Bacterial Ribosome Suggests New Ways for Rational Improvement of Macrolides. Khabibullina NF, Tereshchenkov AG, Komarova ES, Syroegin EA, Shiriaev DI, Paleskava A, Kartsev VG, Bogdanov AA, Konevega AL, Dontsova OA, Sergiev PV, Osterman IA, Polikanov YS. Antimicrob Agents Chemother 63 e02266-18 (2019)
- Synthesis and antibacterial activity of C12 des-methyl ketolides. Lin X, Rico AC, Chu DT, Carroll GL, Barker L, Shawar R, Desai MC, Plattner JJ. Bioorg Med Chem Lett 16 4692-4696 (2006)
- Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 1. Newly generated antibacterial activities against Gram-positive bacteria with erm gene by C-7 modification. Wakiyama Y, Kumura K, Umemura E, Ueda K, Masaki S, Kumura M, Fushimi H, Ajito K. J Antibiot (Tokyo) 69 368-380 (2016)
- Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 2. Synthesis of 7(S)-7-deoxy-7-(4-morpholinocarbonylphenylthio)lincomycin and its 3-dimensional analysis with rRNA. Wakiyama Y, Kumura K, Umemura E, Masaki S, Ueda K, Watanabe T, Yamamoto M, Hirai Y, Ajito K. J Antibiot (Tokyo) 69 428-439 (2016)
- Synthesis of a chlorogenin glycoside library using an orthogonal protecting group strategy. Wang YH, Yeh HW, Wang HW, Yu CC, Guh JH, Liu DZ, Liang PH. Carbohydr Res 375 118-135 (2013)
- The Value of Macrolide-Based Regimens for Community-Acquired Pneumonia. McFarlane A, Sligl W. Curr Infect Dis Rep 17 50 (2015)
- Triphenilphosphonium Analogs of Chloramphenicol as Dual-Acting Antimicrobial and Antiproliferating Agents. Pavlova JA, Khairullina ZZ, Tereshchenkov AG, Nazarov PA, Lukianov DA, Volynkina IA, Skvortsov DA, Makarov GI, Abad E, Murayama SY, Kajiwara S, Paleskava A, Konevega AL, Antonenko YN, Lyakhovich A, Osterman IA, Bogdanov AA, Sumbatyan NV. Antibiotics (Basel) 10 489 (2021)
- A eukaryotic molecular target candidate of roxithromycin: fungal differentiation as a sensitive drug target analysis system. Ishii A, Kumasaka M, Nagashima Y, Nakajima Y, Kuramochi K, Sugawara F, Narukawa M, Kamakura T. Biosci Biotechnol Biochem 77 1539-1547 (2013)
- Comprehensive screening of antimicrobials to control phytoplasma diseases using an in vitro plant-phytoplasma co-culture system. Tanno K, Maejima K, Miyazaki A, Koinuma H, Iwabuchi N, Kitazawa Y, Nijo T, Hashimoto M, Yamaji Y, Namba S. Microbiology (Reading) 164 1048-1058 (2018)
- Design, synthesis and ribosome binding of chloramphenicol nucleotide and intercalator conjugates. Johansson D, Jessen CH, Pøhlsgaard J, Jensen KB, Vester B, Pedersen EB, Nielsen P. Bioorg Med Chem Lett 15 2079-2083 (2005)
- Designer drugs for discerning bugs. Douthwaite S. Proc Natl Acad Sci U S A 107 17065-17066 (2010)
- Identification of macrolide antibiotic-binding Human_p8 protein. Morimura T, Hashiba M, Kameda H, Takami M, Takahama H, Ohshige M, Sugawara F. J Antibiot (Tokyo) 61 291-296 (2008)
- On the structural and functional importance of the highly conserved Glu56 of Thermus thermophilus L4 ribosomal protein. Leontiadou F, Xaplanteri MA, Papadopoulos G, Gerassimou C, Kalpaxis DL, Choli-Papadopoulou T. J Mol Biol 332 73-84 (2003)
- PCR-Based Rapid Identification System Using Bridged Nucleic Acids for Detection of Clarithromycin-Resistant Mycobacterium avium-M. intracellulare Complex Isolates. Hirama T, Shiono A, Egashira H, Kishi E, Hagiwara K, Nakamura H, Kanazawa M, Nagata M. J Clin Microbiol 54 699-704 (2016)
- Preparation of cyclic 2',3'-carbamate derivatives of erythromycin macrolide antibiotics. Heggelund A, Undheim K. Bioorg Med Chem 15 3266-3277 (2007)
- Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida. Breiner-Goldstein E, Eyal Z, Matzov D, Halfon Y, Cimicata G, Baum M, Rokney A, Ezernitchi AV, Lowell AN, Schmidt JJ, Rozenberg H, Zimmerman E, Bashan A, Valinsky L, Anzai Y, Sherman DH, Yonath A. Nucleic Acids Res 49 9560-9573 (2021)
- Structural and functional plasticity of antibiotic resistance nucleotidylyltransferases revealed by molecular characterization of lincosamide nucleotidylyltransferases lnu(A) and lnu(D). Stogios PJ, Evdokimova E, Morar M, Koteva K, Wright GD, Courvalin P, Savchenko A. J Mol Biol 427 2229-2243 (2015)
- Synthesis and biological investigation of new 4''-malonyl tethered derivatives of erythromycin and clarithromycin. Sherman D, Xiong L, Mankin AS, Melman A. Bioorg Med Chem Lett 16 1506-1509 (2006)
- Synthetic oxepanoprolinamide iboxamycin is active against Listeria monocytogenes despite the intrinsic resistance mediated by VgaL/Lmo0919 ABCF ATPase. Brodiazhenko T, Turnbull KJ, Wu KJY, Takada H, Tresco BIC, Tenson T, Myers AG, Hauryliuk V. JAC Antimicrob Resist 4 dlac061 (2022)
- News Telithromycin. Raja A, Lebbos J, Kirkpatrick P. Nat Rev Drug Discov 3 733-734 (2004)
- The central core region of yeast ribosomal protein L11 is important for subunit joining and translational fidelity. Rhodin MH, Rakauskaitė R, Dinman JD. Mol Genet Genomics 285 505-516 (2011)
- A new insight into solid-state conformation of macrolide antibiotics. Miroshnyk I, Mirza S, Zorky PM, Heinämäki J, Yli-Kauhaluoma J, Yliruusi J. Bioorg Med Chem 16 232-239 (2008)
- Adaptation of the 3H-leucine incorporation technique to measure heterotrophic activity associated with biofilm on the blades of the seaweed Sargassum spp. Coelho-Souza SA, Miranda MR, Salgado LT, Coutinho R, Guimaraes JR. Microb Ecol 65 424-436 (2013)
- Effect of ribosome-targeting antibiotics on streptomycin-resistant Mycobacterium mutants in the rpsL gene. Pelchovich G, Zhuravlev A, Gophna U. Int J Antimicrob Agents 42 129-132 (2013)
- Interaction of Chloramphenicol Tripeptide Analogs with Ribosomes. Tereshchenkov AG, Shishkina AV, Tashlitsky VN, Korshunova GA, Bogdanov AA, Sumbatyan NV. Biochemistry (Mosc) 81 392-400 (2016)
- Kinetic and thermodynamic studies of peptidyltransferase in ribosomes from the extreme thermophile Thermus thermophilus. Rodriguez-Correa D, Dahlberg AE. RNA 14 2314-2318 (2008)
- Mechanism of action of a novel series of naphthyridine-type ribosome inhibitors: enhancement of tRNA footprinting at the decoding site of 16S rRNA. Shen LL, Black-Schaefer C, Cai Y, Dandliker PJ, Beutel BA. Antimicrob Agents Chemother 49 1890-1897 (2005)
- Mitochondrial DNA Sequence Variation Associated With Peripheral Nerve Function in the Elderly. Katzman SM, Strotmeyer ES, Nalls MA, Zhao Y, Mooney S, Schork N, Newman AB, Harris TB, Yaffe K, Cummings SR, Liu Y, Tranah GJ, Health, Aging, and Body Composition Study. J Gerontol A Biol Sci Med Sci 70 1400-1408 (2015)
- Multimodal biopanning of T7 phage-displayed peptides reveals angiomotin as a potential receptor of the anti-angiogenic macrolide Roxithromycin. Takakusagi K, Takakusagi Y, Suzuki T, Toizaki A, Suzuki A, Kawakatsu Y, Watanabe M, Saito Y, Fukuda R, Nakazaki A, Kobayashi S, Sakaguchi K, Sugawara F. Eur J Med Chem 90 809-821 (2015)
- Mutations in rpoB That Confer Rifampicin Resistance Can Alter Levels of Peptidoglycan Precursors and Affect β-Lactam Susceptibility. Patel Y, Soni V, Rhee KY, Helmann JD. mBio 14 e0316822 (2023)
- Performance comparison of biofilm and suspended sludge from a sequencing batch biofilm reactor treating mariculture wastewater under oxytetracycline stress. Zheng D, Gao M, Wang Z, She Z, Jin C, Chang Q. Environ Technol 37 2391-2404 (2016)
- Quantum mechanical studies of lincosamides. Kulczycka-Mierzejewska K, Trylska J, Sadlej J. J Mol Model 18 2727-2740 (2012)
- Ribosomes containing mutants of L4 ribosomal protein from Thermus thermophilus display multiple defects in ribosomal functions and sensitivity against erythromycin. Tsagkalia A, Leontiadou F, Xaplanteri MA, Papadopoulos G, Kalpaxis DL, Choli-Papadopoulou T. RNA 11 1633-1639 (2005)
- Stereoselective synthesis of protected 3-amino-3,6-dideoxyaminosugars. Nebot J, Romea P, Urpí F. Org Biomol Chem 10 6395-6403 (2012)
- Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes. Koller TO, Turnbull KJ, Vaitkevicius K, Crowe-McAuliffe C, Roghanian M, Bulvas O, Nakamoto JA, Kurata T, Julius C, Atkinson GC, Johansson J, Hauryliuk V, Wilson DN. Nucleic Acids Res 50 11285-11300 (2022)
- Studying modification of aminoglycoside antibiotics by resistance-causing enzymes via microarray. Disney MD. Methods Mol Biol 808 303-320 (2012)
- Synthesis of novel 4'-substituted 16-membered ring macrolide antibiotics derived from leucomycins. Wang Z, Jian T, Phan LT, Or YS. Bioorg Med Chem Lett 14 519-521 (2004)
- The translating bacterial ribosome at 1.55 Å resolution generated by cryo-EM imaging services. Fromm SA, O'Connor KM, Purdy M, Bhatt PR, Loughran G, Atkins JF, Jomaa A, Mattei S. Nat Commun 14 1095 (2023)
- [Peptide derivatives of tylosin-related macrolides]. Korshunova GA, Sumbatian NV, Fedorova NV, Kuznetsova IV, Shishkina AV, Bogdanov AA. Bioorg Khim 33 235-244 (2007)
- 3-N,N-Dimethylamino-3-deoxy lincomycin: a structure-based hybrid between lincomycin and the desosamine unit of erythromycin. Hanessian S, Kothakonda KK. Bioorg Med Chem 13 5283-5288 (2005)
- A novel class of fast-acting antimalarial agents: Substituted 15-membered azalides. Peric M, Pešić D, Alihodžić S, Fajdetić A, Herreros E, Gamo FJ, Angulo-Barturen I, Jiménez-Díaz MB, Ferrer-Bazaga S, Martínez MS, Gargallo-Viola D, Mathis A, Kessler A, Banjanac M, Padovan J, Bencetić Mihaljević V, Munic Kos V, Bukvić M, Eraković Haber V, Spaventi R. Br J Pharmacol 178 363-377 (2021)
- Cell biology. Lethal traffic jam. Breukink E. Science 325 684-685 (2009)
- Chloramphenicol influence on antioxidant enzymes with preliminary approach on microsomal CYP1A immunopositive-protein in Chamelea gallina. Monari M, Foschi J, Cortesi P, Rosmini R, Cattani O, Serrazanetti GP. Chemosphere 73 272-280 (2008)
- Desosamine in multicomponent reactions. Achatz S, Dömling A. Bioorg Med Chem Lett 16 6360-6362 (2006)
- Dual effect of chloramphenicol peptides on ribosome inhibition. Bougas A, Bougas A, Vlachogiannis IA, Gatos D, Arenz S, Dinos GP. Amino Acids 49 995-1004 (2017)
- Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage. Shen T, Penewit K, Waalkes A, Xu L, Salipante SJ, Nath A, Werth BJ. J Antimicrob Chemother 76 292-296 (2021)
- Investigating the promiscuity of the chloramphenicol nitroreductase from Haemophilus influenzae towards the reduction of 4-nitrobenzene derivatives. Green KD, Fosso MY, Mayhoub AS, Garneau-Tsodikova S. Bioorg Med Chem Lett 29 1127-1132 (2019)
- Macrolides: the plug is out. Gamerdinger M, Deuerling E. Cell 151 469-471 (2012)
- Pharmacokinetics of Tildipirosin in Ewes after Intravenous, Intramuscular and Subcutaneous Administration. Galecio JS, Escudero E, Cerón JJ, Crescenzo G, Marín P. Animals (Basel) 10 E1332 (2020)
- Photolabile anticodon stem-loop analogs of tRNAPhe as probes of ribosomal structure and structural fluctuation at the decoding center. Druzina Z, Cooperman BS. RNA 10 1550-1562 (2004)
- Synthesis and antibacterial activity of 9-oxime ether non-ketolides, and novel binding mode of alkylides with bacterial rRNA. Liang JH, Lv W, Li XL, An K, Cushman M, Wang H, Xu YC. Bioorg Med Chem Lett 23 1387-1393 (2013)
- Synthesis and antibacterial activity of novel 3-O-carbamoyl derivatives of clarithromycin and 11,12-cyclic carbonate azithromycin. Zhang L, Song L, Liu Z, Li H, Lu Y, Li Z, Ma S. Eur J Med Chem 45 915-922 (2010)
- Synthesis and antibacterial activity of novel 4''-O-carbamoyl erythromycin-A derivatives. Qi Y, Jiao B, Ma X, Cui W, Ma S. Arch Pharm (Weinheim) 343 458-464 (2010)
- Synthesis and antibacterial activity of novel lincomycin derivatives. II. Exploring (7S)-7-(5-aryl-1,3,4-thiadiazol-2-yl-thio)-7-deoxylincomycin derivatives. Kumura K, Wakiyama Y, Ueda K, Umemura E, Watanabe T, Kumura M, Yoshida T, Ajito K. J Antibiot (Tokyo) 70 655-663 (2017)
- Synthesis and structure-activity relationships of novel lincomycin derivatives part 3: discovery of the 4-(pyrimidin-5-yl)phenyl group in synthesis of 7(S)-thiolincomycin analogs. Wakiyama Y, Kumura K, Umemura E, Masaki S, Ueda K, Sato Y, Watanabe T, Hirai Y, Ajito K. J Antibiot (Tokyo) 70 52-64 (2017)
- [Amino acid and peptide derivatives of the tylosin family of macrolide antibiotics modified at the aldehyde group]. Sumbatian NV, Kuznetsova IV, Karpenko VV, Fedorova NV, Chertkov VA, Korshunova GA, Bogdanov AA. Bioorg Khim 36 265-276 (2010)
- A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid. Perlaza-Jiménez L, Tan KS, Piper SJ, Johnson RM, Bamert RS, Stubenrauch CJ, Wright A, Lupton D, Lithgow T, Belousoff MJ. Microbiol Spectr 10 e0058322 (2022)
- A microbiological assay to estimate the antimicrobial activity of parenteral tildipirosin against foodborne pathogens and commensals in the colon of beef cattle and pigs. Rose M, Pridmore A, Shaw A, Wilhelm C, Menge M, Kilp S, Röpke R, Nürnberger M. J Vet Pharmacol Ther 39 277-286 (2016)
- A quantitative systems pharmacology (QSP) model for Pneumocystis treatment in mice. Liu GS, Ballweg R, Ashbaugh A, Zhang Y, Facciolo J, Cushion MT, Zhang T. BMC Syst Biol 12 77 (2018)
- Editorial Back to the future: the ribosome as an antibiotic target. Franceschi F. Future Microbiol 2 571-574 (2007)
- Comparative Analysis of Chloramphenicol-Resistant Enterococcus faecalis Isolated from Dairy Companies in Korea. Bae SH, Yoon S, Kim K, Kim YB, Lee YJ. Vet Sci 8 143 (2021)
- Cryo-EM structure of Mycobacterium tuberculosis 50S ribosomal subunit bound with clarithromycin reveals dynamic and specific interactions with macrolides. Zhang W, Li Z, Sun Y, Cui P, Liang J, Xing Q, Wu J, Xu Y, Zhang W, Zhang Y, He L, Gao N. Emerg Microbes Infect 11 293-305 (2022)
- Determination of the secondary structure of group II bulge loops using the fluorescent probe 2-aminopurine. Dishler AL, McMichael EL, Serra MJ. RNA 21 975-984 (2015)
- Letter Enzymatic Synthesis of the C-Glycosidic Moiety of Nogalamycin R. Siitonen V, Nji Wandi B, Törmänen AP, Metsä-Ketelä M. ACS Chem Biol 13 2433-2437 (2018)
- Inhibition of Escherichia coli ribosome subunit dissociation by chloramphenicol and Blasticidin: a new mode of action of the antibiotics. Pathak BK, Mondal S, Barat C. Lett Appl Microbiol 64 79-85 (2017)
- Insights into resistance against lincosamide antibiotics. Sundlov JA, Gulick AM. Structure 17 1549-1550 (2009)
- Molecular mechanics (MM3(pi)) conformational analysis of molecules containing conjugated pi-electron fragments: Leucomycin-V. Kotev MI, Ivanov PM. Chirality 20 400-410 (2008)
- Mutational analysis of basic residues in the N-terminus of the rRNA:m6A methyltransferase ErmC'. Maravić G, Bujnicki JM, Flögel M. Folia Microbiol (Praha) 49 3-7 (2004)
- NMR characterisation of a highly conserved secondary structural RNA motif of Halobacterium halobium 23S rRNA. King J, Shammas C, Nareen M, Lelli M, Ramesh V. Org Biomol Chem 11 3382-3392 (2013)
- Preparation and antibacterial activity of cyclic 2',3'-carbamate derivatives of azithromycin. Heggelund A, Rømming C, Undheim K. Eur J Med Chem 43 1657-1664 (2008)
- Recent Trends in Synthesis of Chloramphenicol New Derivatives. Tevyashova AN. Antibiotics (Basel) 10 370 (2021)
- Solvent effect on the synthesis of clarithromycin: a molecular dynamics study. Duran D, Aviyente V, Baysa C. J Comput Aided Mol Des 18 145-154 (2004)
- Synthesis and activity of new macrolones: conjugates between 6(7)-(2'-aminoethyl)-amino-1-cyclopropyl-3-carboxylic acid (2'-hydroxyethyl) amides and 4″-propenoyl-azithromycin. Kapić S, Fajdetić A, Koštrun S, Cikoš A, Paljetak HČ, Antolović R, Holmes DJ, Alihodžić S. Bioorg Med Chem 19 7270-7280 (2011)
- Synthesis and antibacterial activity of novel lincomycin derivatives. III. Optimization of a phenyl thiadiazole moiety. Kumura K, Wakiyama Y, Ueda K, Umemura E, Watanabe T, Yamamoto M, Yoshida T, Ajito K. J Antibiot (Tokyo) (2017)
- Synthesis and evaluation of chloramphenicol homodimers: molecular target, antimicrobial activity, and toxicity against human cells. Kostopoulou ON, Magoulas GE, Papadopoulos GE, Mouzaki A, Dinos GP, Papaioannou D, Kalpaxis DL. PLoS One 10 e0134526 (2015)
- Telithromycin in the treatment of acute bacterial sinusitis, acute exacerbations of chronic bronchitis, and community-acquired pneumonia. Zhanel GG, Hisanaga T, Wierzbowski A, Hoban DJ. Ther Clin Risk Manag 2 59-75 (2006)
- Update on carbohydrate-containing antibacterial agents. Schitter G, Wrodnigg TM. Expert Opin Drug Discov 4 315-356 (2009)
- A SAM-dependent methyltransferase cotranscribed with arsenate reductase alters resistance to peptidyl transferase center-binding antibiotics in Azospirillum brasilense Sp7. Singh S, Singh C, Tripathi AK. Appl Microbiol Biotechnol 98 4625-4636 (2014)
- A method for selecting cis-acting regulatory sequences that respond to small molecule effectors. Allas U, Tenson T. BMC Mol Biol 11 56 (2010)
- Chloramphenicol inhibits eukaryotic Ser/Thr phosphatase and infection-specific cell differentiation in the rice blast fungus. Nozaka A, Nishiwaki A, Nagashima Y, Endo S, Kuroki M, Nakajima M, Narukawa M, Kamisuki S, Arazoe T, Taguchi H, Sugawara F, Kamakura T. Sci Rep 9 9283 (2019)
- Classification of ligand molecules in PDB with graph match-based structural superposition. Shionyu-Mitsuyama C, Hijikata A, Tsuji T, Shirai T. J Struct Funct Genomics 17 135-146 (2016)
- Design, synthesis and biological evaluation of azithromycin glycosyl derivatives as potential antibacterial agents. Zhang L, Chai X, Wang B, Yu S, Hu H, Zou Y, Zhao Q, Meng Q, Wu Q. Bioorg Med Chem Lett 23 5057-5060 (2013)
- Determination of the three-dimensional, solution-phase structure of the macrolide antibiotic oxolide in CD2Cl2 and D2O from NMR constraints. Steinmetz WE, Sparrow A, Somsouk M. Magn Reson Chem 43 16-20 (2005)
- Efficacy and Safety of VB-1953 Topical Gel in Non-Responder Acne Patients with Clindamycin-Resistant Cutibacterium acnes. Batra R, Sadhasivam S, Saini S, Gupta S, Bisen RKS, Sinha M, Ghosh S, Jain S. Drugs R D 20 95-104 (2020)
- research-article Functional dynamics of proteins. Yang LW, Matysiak S, Hsu ST, Mustata Wilson G, Joti Y. Comput Math Methods Med 2012 242903 (2012)
- Identification and Characterization of a Chloroplast-Targeted Obg GTPase in Dendrobium officinale. Chen J, Deng F, Deng M, Han J, Chen J, Wang L, Yan S, Tong K, Liu F, Tian M. DNA Cell Biol 35 802-811 (2016)
- In vitro antibacterial activity of α-methoxyimino acylide derivatives against macrolide-resistant pathogens and mutation analysis in 23S rRNA. Sugiyama H, Yoshida I, Ueki M, Tanabe K, Manaka A, Hiramatsu K. J Antibiot (Tokyo) 70 264-271 (2017)
- Mechanism of translation based on intersubunit complementarities of ribosomal RNAs and tRNAs. Nagano K, Nagano N. J Theor Biol 245 644-668 (2007)
- Molecular dynamics simulations suggest why the A2058G mutation in 23S RNA results in bacterial resistance against clindamycin. Kulczycka-Mierzejewska K, Sadlej J, Trylska J. J Mol Model 24 191 (2018)
- Protein biosynthesis on ribosomes in molecular resolution: Nobel Prize for chemistry 2009 goes to three chemical biologists. Sprinzl M, Erdmann VA. Chembiochem 10 2851-2853 (2009)
- Radiostability of florfenicol in the solid state. Marciniec B, Stawny M, Kachlicki P, Jaroszkiewicz E, Needham M. Anal Sci 25 1255-1260 (2009)
- Rapid Structure Determination of Bioactive 4″-Tetrahydrofurfuryl Macrozone Reaction Mixture Components by LC-SPE/Cryo NMR and MS. Habinovec I, Mikulandra I, Sekula LE, Gašperov J, Kazazić S, Novak P. Molecules 26 6316 (2021)
- Structural basis for motilin and erythromycin recognition by motilin receptor. You C, Zhang Y, Xu Y, Xu P, Li Z, Li H, Huang S, Chen Z, Li J, Xu HE, Jiang Y. Sci Adv 9 eade9020 (2023)
- Studies of lincosamide formation complete the biosynthetic pathway for lincomycin A. Wang SA, Lin CI, Zhang J, Ushimaru R, Sasaki E, Liu HW. Proc Natl Acad Sci U S A 117 24794-24801 (2020)
- Sugar-Pirating as an Enabling Platform for the Synthesis of 4,6-Dideoxyhexoses. Zhang Y, Zhang J, Ponomareva LV, Cui Z, Van Lanen SG, Thorson JS. J Am Chem Soc 142 9389-9395 (2020)
- Synthesis and antibacterial activity of novel 4''-carbamates of 6,11-di-O-methylerythromycin A. Wu Z, Lu Y, Luo M, He X, Xiao Y, Yang J, Pan Y, Qiu G, Xu Y, Huang W, Long P, Li R, Hu X. J Antibiot (Tokyo) 63 343-350 (2010)
- Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 4: synthesis of novel lincomycin analogs modified at the 6- and 7-positions and their potent antibacterial activities. Wakiyama Y, Kumura K, Umemura E, Ueda K, Watanabe T, Yamada K, Okutomi T, Ajito K. J Antibiot (Tokyo) 70 888-906 (2017)
- Two approaches to the use of benzo[c][1,2]oxaboroles as active fragments for synthetic transformation of clarithromycin. Lapa GB, Mirchink EP, Isakova EB, Preobrazhenskaya MN. J Enzyme Inhib Med Chem 32 452-456 (2017)
- Yersinia pseudotuberculosis doxycycline tolerance strategies include modulating expression of genes involved in cell permeability and tRNA modifications. Alvarez-Manzo HS, Davidson RK, Van Cauwelaert de Wyels J, Cotten KL, Nguyen BH, Xiao M, Zhu Z, Anthony J, van Opijnen T, Davis KM. PLoS Pathog 18 e1010556 (2022)
- A Rapid Screening Assay for Clarithromycin-Resistant Mycobacterium avium Complex Using Melting Curve Analysis with Nonfluorescent Labeled Probes. Aoki A, Jinno H, Ogawa K, Nakagawa T, Inagaki T, Wajima T, Okamoto Y, Uchiya KI. Microbiol Spectr 11 e0432622 (2023)
- Antibiotics: Precious Goods in Changing Times. Sass P. Methods Mol Biol 2601 3-26 (2023)
- Brazilian Clinical Strains of Actinobacillus pleuropneumoniae and Pasteurella multocida: Capsular Diversity, Antimicrobial Susceptibility (In Vitro) and Proof of Concept for Prevention of Natural Colonization by Multi-Doses Protocol of Tildipirosin. Kuchiishi SS, Ramos Prigol S, Bresolin E, Fernandes Lenhard B, Pissetti C, García-Iglesias MJ, Gutiérrez-Martín CB, Martínez-Martínez S, Kreutz LC, Frandoloso R. Antibiotics (Basel) 12 1658 (2023)
- Changes in the level of poly(Phe) synthesis in Escherichia coli ribosomes containing mutants of L4 ribosomal protein from Thermus thermophilus can be explained by structural changes in the peptidyltransferase center: a molecular dynamics simulation analysis. Papadopoulos G, Grudinin S, Kalpaxis DL, Choli-Papadopoulou T. Eur Biophys J 35 675-683 (2006)
- Conformational adaptation of UNCG loops upon crowding. Meyer M, Walbott H, Oliéric V, Kondo J, Costa M, Masquida B. RNA 25 1522-1531 (2019)
- Conformational space of clindamycin studied by ab initio and full-atom molecular dynamics. Kulczycka-Mierzejewska K, Trylska J, Sadlej J. J Mol Model 22 20 (2016)
- Differential activity profiles of translation inhibitors in whole-cell and cell-free approaches. Weidlich M, Klammt C, Bernhard F, Karas M, Stein T. Lett Appl Microbiol 46 155-159 (2008)
- E pluribus tres: the 2009 nobel prize in chemistry. Carter CW. Structure 17 1558-1561 (2009)
- Intercepting biological messages: Antibacterial molecules targeting nucleic acids during interbacterial conflicts. Hespanhol JT, Karman L, Sanchez-Limache DE, Bayer-Santos E. Genet Mol Biol 46 e20220266 (2023)
- Proteostasis modulators with discriminating taste. Paavilainen VO, Taunton J. Chem Biol 20 144-145 (2013)
- Rational prioritization strategy allows the design of macrolide derivatives that overcome antibiotic resistance. König G, Sokkar P, Pryk N, Heinrich S, Möller D, Cimicata G, Matzov D, Dietze P, Thiel W, Bashan A, Bandow JE, Zuegg J, Yonath A, Schulz F, Sanchez-Garcia E. Proc Natl Acad Sci U S A 118 e2113632118 (2021)
- Refinement of a low-resolution crystal structure to better understand erythromycin interactions on large ribosomal subunit. Wahab HA, Yam WK, Samian MR, Najimudin N. J Biomol Struct Dyn 26 131-146 (2008)
- Screening of Novel Antimicrobial Diastereomers of Azithromycin-Thiosemicarbazone Conjugates: A Combined LC-SPE/Cryo NMR, MS/MS and Molecular Modeling Approach. Habinovec I, Mikulandra I, Pranjić P, Kazazić S, Paljetak HČ, Barišić A, Bertoša B, Bukvić M, Novak P. Antibiotics (Basel) 11 1738 (2022)
- Structural conservation of antibiotic interaction with ribosomes. Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO, Morici M, Beckert B, Myasnikov AG, Grubmüller H, Nováček J, Wilson DN. Nat Struct Mol Biol 30 1380-1392 (2023)
- Targeting malaria parasites with novel derivatives of azithromycin. Burns AL, Sleebs BE, Gancheva M, McLean KT, Siddiqui G, Venter H, Beeson JG, O'Handley R, Creek DJ, Ma S, Frölich S, Goodman CD, McFadden GI, Wilson DW. Front Cell Infect Microbiol 12 1063407 (2022)
- Thermus thermophilus L4 ribosomal protein: purification and sensitivity alteration against erythromycin of E. coli cells harboring a single amino acid mutant of TthL4 within its extended loop. Leontiadou F, Tsagkalia A, Choli-Papadopoulou T. Amino Acids 33 463-468 (2007)
- Unfolded protein exhibits antiassociation activity toward the 50S subunit facilitating 70S ribosome dissociation. Pathak BK, Banerjee S, Mondal S, Chakraborty B, Sengupta J, Barat C. FEBS J 284 3915-3930 (2017)