› 1jzb

X-ray diffraction
2.81Å resolution

Crystal Structure of Variant 2 Scorpion Toxin from Centruroides sculpturatus Ewing

Released:
DOI: 10.2210/pdb1jzb/pdb
PDB entry 1jzb coloured by chain, front view.
PDB entry 1jzb coloured by chain, side view.
PDB entry 1jzb coloured by chain, top view.
Source organism: Centruroides sculpturatus
Primary publication:
Structure of variant 2 scorpion toxin from Centruroides sculpturatus Ewing.
Cook WJ, Zell A, Watt DD, Ealick SE
Protein Sci 11 479-86 (2002)
PMID: 11847271

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134330 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Toxin CsEv2 Chain: A
Molecule details ›
Chain: A
Length: 66 amino acids
Theoretical weight: 7.18 KDa
Source organism: Centruroides sculpturatus
UniProt:
  • Canonical: P01493 (Residues: 20-85; Coverage: 97%)
Sequence domains: Scorpion toxin-like domain
Structure domains: Knottin, scorpion toxin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OTHER
Spacegroup: P3221
Unit cell:
a: 48.8Å b: 48.8Å c: 43.7Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.233 0.233 0.277

Quick links

Citations

2 review citations

Voltage-gated ion channels and gating modifier toxins.
Catterall et al. (2007)
1 more

5 mentions without citation

A robust bulk-solvent correction and anisotropic scaling procedure.
Afonine et al. (2005)
4 more