X-ray diffraction
2.54Å resolution

Crystal structure of the multidrug binding protein QacR bound to dequalinium


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
HTH-type transcriptional regulator QacR Chains: A, B, D, E
Molecule details ›
Chains: A, B, D, E
Length: 188 amino acids
Theoretical weight: 22.15 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
  • Canonical: P0A0N4 (Residues: 1-188; Coverage: 100%)
Gene names: SAP100B_005, SAP104C_022, qacR
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P42212
Unit cell:
a: 172Å b: 172Å c: 94.6Å
α: 90° β: 90° γ: 90°
R R work R free
0.209 0.209 0.256
Expression system: Escherichia coli