X-ray diffraction
2.9Å resolution

Crystal structure of a cooperative QacR-DNA complex


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
HTH-type transcriptional regulator QacR Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 194 amino acids
Theoretical weight: 22.98 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
  • Canonical: P0A0N4 (Residues: 1-188; Coverage: 100%)
Gene names: SAP100B_005, SAP104C_022, qacR
Sequence domains:
Structure domains:
QACA operator Chains: E, F
Molecule details ›
Chains: E, F
Length: 28 nucleotides
Theoretical weight: 8.6 KDa
Source organism: Staphylococcus aureus
Expression system: Not provided

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P65
Unit cell:
a: 174.7Å b: 174.7Å c: 151.95Å
α: 90° β: 90° γ: 120°
R R work R free
0.217 0.222 0.258
Expression systems:
  • Escherichia coli
  • Not provided