1jsg

X-ray diffraction
2.5Å resolution

CRYSTAL STRUCTURE OF P14TCL1, AN ONCOGENE PRODUCT INVOLVED IN T-CELL PROLYMPHOCYTIC LEUKEMIA, REVEALS A NOVEL B-BARREL TOPOLOGY

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
T-cell leukemia/lymphoma protein 1A Chain: A
Molecule details ›
Chain: A
Length: 114 amino acids
Theoretical weight: 13.48 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P56279 (Residues: 1-114; Coverage: 100%)
Gene names: TCL1, TCL1A
Sequence domains: TCL1/MTCP1 family
Structure domains: TCL1/MTCP1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: I222
Unit cell:
a: 38.897Å b: 82.839Å c: 117.726Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.192 0.259