1jrr

X-ray diffraction
1.6Å resolution

HUMAN PLASMINOGEN ACTIVATOR INHIBITOR-2.[LOOP (66-98) DELETIONMUTANT] COMPLEXED WITH PEPTIDE MIMIckING THE REACTIVE CENTER LOOP

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Plasminogen activator inhibitor 2 Chain: A
Molecule details ›
Chain: A
Length: 382 amino acids
Theoretical weight: 43.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05120 (Residues: 1-415; Coverage: 92%)
Gene names: PAI2, PLANH2, SERPINB2
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:
Plasminogen activator inhibitor 2 Chain: P
Molecule details ›
Chain: P
Length: 15 amino acids
Theoretical weight: 1.31 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P05120 (Residues: 367-380; Coverage: 3%)
Gene names: PAI2, PLANH2, SERPINB2

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P21212
Unit cell:
a: 93.139Å b: 104.16Å c: 41.395Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.197 0.225
Expression systems:
  • Escherichia coli
  • Not provided