Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- DNA clamp superfamily
- DNA polymerase III, beta sliding clamp
- P-loop containing nucleoside triphosphate hydrolase
- DNA polymerase III subunit delta, C-terminal
- DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
- DNA polymerase III delta, N-terminal
- DNA polymerase III, delta subunit
- DNA polymerase III, beta sliding clamp, C-terminal
2 more domains
Structure analysis Details
Assemblies composition:
Assembly name:
PDBe Complex ID:
PDB-CPX-141821 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Beta sliding clamp
Molecule details ›
Chains: A, B
Length: 366 amino acids
Theoretical weight: 40.55 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 366 amino acids
Theoretical weight: 40.55 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical:
P0A988 (Residues: 1-366; Coverage: 100%)
Sequence domains:
- DNA polymerase III beta subunit, N-terminal domain
- DNA polymerase III beta subunit, central domain
- DNA polymerase III beta subunit, C-terminal domain
DNA polymerase III subunit delta
Molecule details ›
Chains: C, D
Length: 343 amino acids
Theoretical weight: 38.75 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 343 amino acids
Theoretical weight: 38.75 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: P28630 (Residues: 1-343; Coverage: 100%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 19-ID
Spacegroup:
C2
Expression system: Escherichia coli
