Structure analysis

Crystal Structure of Murine Tcl1 at 2.5 Resolution

X-ray diffraction
2.5Å resolution
Source organism: Mus musculus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 11600 Å2
Buried surface area: 900 Å2
Dissociation area: 450 Å2
Dissociation energy (ΔGdiss): -5 kcal/mol
Dissociation entropy (TΔSdiss): 11 kcal/mol
Interface energy (ΔGint): -4 kcal/mol
Symmetry number: 1

Macromolecules

Chains: A, B
Length: 116 amino acids
Theoretical weight: 14.1 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P56280 (Residues: 1-116; Coverage: 100%)
Gene names: Tcl1, Tcl1a
Pfam: TCL1/MTCP1 family
InterPro:
CATH: TCL1/MTCP1
SCOP: Oncogene products

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