X-ray diffraction
2.85Å resolution

Crystal Structure of Fab-Estradiol Complexes


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig lambda-1 chain C region Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 212 amino acids
Theoretical weight: 22.74 KDa
Source organism: Mus musculus
  • Canonical: P01843 (Residues: 1-102; Coverage: 97%)
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
monoclonal anti-estradiol 10G6D6 Fab heavy chain Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 218 amino acids
Theoretical weight: 23.54 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 70.2Å b: 192.9Å c: 71.12Å
α: 90° β: 92.93° γ: 90°
R R work R free
0.198 0.198 0.253